Pardessus Otero Ana, Rafecas-Codern Albert, Porcel José M, Serra-Mitjà Pere, Ferreiro Lucía, Botana-Rial Maribel, Ramos-Hernández Cristina, Brenes José Manuel, Canales Lydia, Camacho Valle, Romero-Romero Beatriz, Trujillo Juan Carlos, Martinez Elisabeth, Cases Enrique, Barba Andrés, Majem Margarita, Güell Ernest, Pajares Virginia
Interventional Pulmonology, Respiratory Medicine Department, Hospital de la Santa Creu i Sant Pau, Universitat Autónoma Barcelona (UAB), Barcelona, Spain.
Chronic Respiratory Disease Group (GREC), Institut de Recerca Sant Pau (IR SANT PAU), Spain.
Open Respir Arch. 2024 Jun 19;6(4):100349. doi: 10.1016/j.opresp.2024.100349. eCollection 2024 Oct-Dec.
Malignant pleural effusion (MPE) has become an increasingly prevalent complication in oncological patients, negatively impacting their quality of life and casting a shadow over their prognosis. Owing to the pathophysiological mechanisms involved and the heterogeneous nature of the underlying disease, this entity is both a diagnostic and therapeutic challenge. Advances in the understanding of MPE have led to a shift in the treatment paradigm towards a more personalized approach. This article provides a comprehensive review and update on the pathophysiology of MPE and describes the diagnostic tools and the latest advances in the treatment of this complex clinical entity.
恶性胸腔积液（MPE）已成为肿瘤患者中日益普遍的并发症，对其生活质量产生负面影响，并给预后蒙上阴影。由于涉及的病理生理机制以及基础疾病的异质性，这一病症在诊断和治疗方面均具有挑战性。对MPE认识的进展已导致治疗模式向更个性化的方法转变。本文对MPE的病理生理学进行了全面综述和更新，并描述了该复杂临床病症的诊断工具和治疗方面的最新进展。
