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脱离有创机械通气:荷兰重症监护病房的全国性调查。

Liberation from invasive mechanical ventilation: a nationwide survey among intensive care units in the Netherlands.

作者信息

Groenland Carline N L, Janssen Matthijs L, van den Bosch Kim S, Baggen Vivan J M, Heunks Leo, Endeman Henrik, Wils Evert-Jan

机构信息

Intensive Care, Franciscus Gasthuis en Vlietland, Rotterdam, The Netherlands.

Intensive Care, Erasmus MC, Rotterdam, The Netherlands.

出版信息

BMJ Open Respir Res. 2025 Jul 21;12(1):e002868. doi: 10.1136/bmjresp-2024-002868.

Abstract

BACKGROUND

Liberation from invasive mechanical ventilation is a milestone in critical care, but approaches vary. This survey aimed to describe current ventilator liberation practices, relate them to available evidence, and identify areas for improvement.

METHODS

A survey was performed among Dutch intensive care unit (ICU) sites. The survey evaluated practice in seven domains of ventilator liberation: protocol availability, transition from controlled to assisted ventilation, spontaneous breathing trials (SBT), cuff-leak test, postextubation support, weaning failure and tracheostomised weaning.

RESULTS

The survey response rate was 93% (132/142), representing 97% (69/71) of Dutch ICUs. Protocols for postextubation support and weaning failure were available in less than half of the ICUs (44% and 49%, respectively). The transition from controlled to assisted ventilation is regularly evaluated daily in 78% of ICUs. Assisted ventilation tolerance is mainly assessed by clinical signs, respiratory parameters and non-invasive manoeuvres that assess respiratory drive (P). SBTs are regularly performed in 58% of ICUs, using one or more of the following methods: T-piece (52%), pressure support+positive end expiratory pressure (32%) and continuous positive airway pressure (28%). Cuff-leak tests are seldom performed (1.4%), predominantly in cases of intubation for upper-airway obstruction (92%). Postextubation respiratory support with high-flow nasal oxygen or non-invasive ventilation is used at least as often with therapeutic (43%/13%) rather than preventive (35%/4%) of facilitative intent (29%/3%). Delirium screening (87%) and reconsidering sedation (84%) are frequently assessed in case of weaning failure. Regular use of closed-loop ventilation is reported in a minority of ICUs throughout the process of ventilator liberation (3-9%).

CONCLUSIONS

Various aspects of ventilator liberation practices show only limited alignment with existing guidelines. The results of this survey pinpoint areas to prioritise in guideline and practice improvement.

摘要

背景

从有创机械通气中撤机是重症监护中的一个里程碑,但方法各不相同。本调查旨在描述当前的呼吸机撤机实践,将其与现有证据相关联,并确定改进领域。

方法

对荷兰重症监护病房(ICU)进行了一项调查。该调查评估了呼吸机撤机七个领域的实践情况:方案可用性、从控制通气到辅助通气的转换、自主呼吸试验(SBT)、套囊漏气试验、拔管后支持、撤机失败和气管切开患者的撤机。

结果

调查回复率为93%(132/142),占荷兰ICU的97%(69/71)。不到一半的ICU有拔管后支持和撤机失败的方案(分别为44%和49%)。78%的ICU每天定期评估从控制通气到辅助通气的转换。辅助通气耐受性主要通过临床体征、呼吸参数和评估呼吸驱动的非侵入性操作(P)来评估。58%的ICU定期进行SBT,使用以下一种或多种方法:T形管(52%)、压力支持+呼气末正压(32%)和持续气道正压(28%)。很少进行套囊漏气试验(1.4%),主要用于上气道梗阻插管病例(92%)。拔管后使用高流量鼻氧或无创通气进行呼吸支持时,至少同样常用于治疗目的(43%/13%)而非预防目的(35%/4%)或促进目的(29%/3%)。在撤机失败时,经常评估谵妄筛查(87%)和重新考虑镇静(84%)。在呼吸机撤机的整个过程中,少数ICU报告经常使用闭环通气(3-9%)。

结论

呼吸机撤机实践的各个方面与现有指南的一致性有限。本次调查结果指出了在指南和实践改进中应优先考虑的领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb7d/12281335/a63d2c2b7d03/bmjresp-12-1-g001.jpg

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