Krukow Paweł, Kopiś-Posiej Natalia, Rodríguez-González Víctor, Mazur Michał, Gómez Carlos, Poza Jesús
Department of Clinical Neuropsychiatry, Medical University of Lublin, Ul. Głuska 1, Lublin, 20-439, Poland.
Department of Experimental Psychology, Institute of Psychology, The John Paul II, Catholic University of Lublin, Lublin, Poland.
Sci Rep. 2025 Jul 21;15(1):26468. doi: 10.1038/s41598-025-12558-7.
Verbal fluency tests (VFTs) are commonly used tasks for analyzing frontal cortex activation imagined by functional near-infrared spectroscopy (fNIRS). Some new VFT versions have been developed to strengthen the test's executive character. However, these modified tasks were not used to recognize whether they activate cortical areas significantly differently compared with typical tasks. We introduced a modified VFT version consisting of the necessity to produce words according to one phonemic criterion and exclude others according to another phonemic criterion to establish frontal cortex task-dependent hemodynamic activity for the proposed new task. The analysis was conducted by comparison with a typical initial letter fluency task in a group of 35 students. Behavioral results showed between-tasks differences in productivity during the initial phase of performance. Increased oxygenated hemoglobin (oxy-Hb) concentration in lateral and frontopolar regions was noted in both analyzed tasks, but oxy-Hb suppression has been observed in the middle/superior frontal cortex only for the new one. Such an arrangement of selective metabolic activation and inactivation suggests that the brain's adaptation to increased processing demands may consist of restraining the oxygen intake of the neuronal region, which activity is not necessary to perform a task.
语言流畅性测试（VFTs）是分析功能性近红外光谱（fNIRS）所设想的额叶皮质激活的常用任务。已经开发了一些新的VFT版本来强化测试的执行特征。然而，这些修改后的任务并未用于识别与典型任务相比，它们是否会显著激活不同的皮质区域。我们引入了一个修改后的VFT版本，该版本要求根据一个音素标准生成单词，并根据另一个音素标准排除其他单词，以确定所提出的新任务的额叶皮质任务依赖血流动力学活动。通过与一组35名学生的典型首字母流畅性任务进行比较来进行分析。行为结果显示在表现的初始阶段任务之间在生产率上存在差异。在两个分析任务中均观察到外侧和额极区域的氧合血红蛋白（oxy-Hb）浓度增加，但仅在新任务中，在中/上额叶皮质观察到了oxy-Hb抑制。这种选择性代谢激活和失活的安排表明，大脑对增加的处理需求的适应可能包括限制神经元区域的氧气摄入，而该区域的活动对于执行任务并非必要。
