Zu Tingting, Gao Meng, Liu Baohe, Zhang Xuejing, Wu Fuling
Pediatrics Department, Binzhou Medical University Hospital, Binzhou 256600, China.
Medicine (Baltimore). 2025 Jul 18;104(29):e43416. doi: 10.1097/MD.0000000000043416.
The emergence of extracellular vesicles with nanostructure characteristics signifies a novel acellular therapeutic approach at the nanoscale, influencing cellular processes such as proliferation, differentiation, and apoptosis, as well as serving as vehicles for precise drug delivery. Substantial evidence supports their involvement in tissue regeneration, immune modulation, targeted tumor diagnosis and therapy effects. This review seeks to establish a theoretical framework for investigating the impact of extracellular vesicles derived from mesenchymal stem cells on respiratory system disorders in future research.
具有纳米结构特征的细胞外囊泡的出现标志着一种新型的纳米级无细胞治疗方法，它影响细胞增殖、分化和凋亡等细胞过程，还可作为精确药物递送的载体。大量证据支持它们参与组织再生、免疫调节、靶向肿瘤诊断和治疗效果。本综述旨在建立一个理论框架，以便在未来研究中探究间充质干细胞来源的细胞外囊泡对呼吸系统疾病的影响。
