Cavens Thuy Thanh, de Vries Janneke, Verleisdonk-Bolhaar Suzanne, Buil Jochem B, van Marion Arienne
Department of Pathology VieCuri, Tegelseweg 210, 5912 BL Venlo, Netherlands.
Department of Medical Microbiology Viecuri, Tegelseweg 210, 5912 BL Venlo, Netherlands.
Med Mycol Case Rep. 2025 Jul 14;49:100717. doi: 10.1016/j.mmcr.2025.100717. eCollection 2025 Sep.
is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy revealed pigmented, septate hyphae without muriform cells, consistent with a diagnosis of phaeohyphomycosis. Surgical excision and culture confirmed . Afterwards the patient received a three-week course of itraconazole, which led to infection resolution. This report and review of literature underscores the diagnostic and therapeutic approaches for managing deep cutaneous infections caused by .
是一种暗色真菌，很少引起皮肤和呼吸道感染。我们报告一例在荷兰的69岁IV期乳腺癌患者，该患者正在接受地塞米松治疗，发生了深部皮肤感染。患者出现皮肤斑块病变，活检显示有色素沉着、有隔菌丝，无砖格状细胞，符合暗色丝孢霉病的诊断。手术切除和培养得到了证实。之后患者接受了为期三周的伊曲康唑治疗，感染得到缓解。本报告及文献综述强调了由……引起的深部皮肤感染的诊断和治疗方法。
