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纽芬兰与拉布拉多省播散性淋菌性关节炎的首例病例报告。

First case report of disseminated gonococcal arthritis in Newfoundland and Labrador.

作者信息

Karsenti Nessika, Nelder Matthew, LeMeissurier Jennifer, Bourassa-Blanchette Samuel, Taylor Robert M

机构信息

Faculty of Medicine, Memorial University, St. John's, NL, Canada.

Newfoundland and Labrador Health Services, St. John's, NL, Canada.

出版信息

Access Microbiol. 2025 Jan 30;7(1). doi: 10.1099/acmi.0.000807.v3. eCollection 2025.

Abstract

Disseminated gonococcal infections (DGIs) are a rare but often debilitating complication of infections. Often presenting as arthritis-dermatitis syndrome, true suppurative joint infections are an even more rare form of DGI. Here, we present the first known case of DGI in Newfoundland and Labrador in over 10 years. A 50-year-old man who is known to inject drugs with multiple housing and social challenges presented to the emergency department with a 2-day history of an isolated, painful, erythematous knee. After being assessed by orthopaedics and undergoing an operative debridement, intraoperative cultures grew . He was treated with intravenous ceftriaxone, and his course in hospital was complicated by inadequate pain control and a lack of stable housing. Although rare, DGIs need to remain on every clinician's differential for septic arthritis, given the increasing prevalence of gonorrhoeal infections in Canada, particularly in Newfoundland and Labrador. In addition, patients who are at risk of delaying accessing care, such as people who inject drugs and unhoused individuals, are at higher risk of complicated hospital stays.

摘要

播散性淋球菌感染(DGIs)是一种罕见但常使人衰弱的感染并发症。通常表现为关节炎-皮炎综合征,真正的化脓性关节感染是DGI更罕见的一种形式。在此,我们报告了纽芬兰和拉布拉多省10多年来首例已知的DGI病例。一名50岁男子,有注射毒品史,面临多种住房和社会问题,因孤立性、疼痛性、红斑性膝关节2天病史就诊于急诊科。经骨科评估并接受手术清创后,术中培养出……。他接受了静脉注射头孢曲松治疗,住院期间因疼痛控制不佳和缺乏稳定住房而病情复杂。尽管罕见,但鉴于加拿大淋病感染率不断上升,尤其是在纽芬兰和拉布拉多省,DGIs仍需列入每位临床医生对脓毒性关节炎的鉴别诊断中。此外,有延迟就医风险的患者,如注射毒品者和无家可归者,住院期间出现并发症的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2f/12281791/787165dc1ae6/acmi-7-00807-g001.jpg

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