AlTurki Ahmed, Toscani Bruno, Vidal Alejandro, Diaz Sergio, Lima Pedro Y, Garcia Daniel, Neumann Marcio, Faganello Lucas, Barbosa Rodrigo Silva, Bernier Martin L, Joza Jacqueline, Essebag Vidal
Department of Medicine, Division of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada.
CJC Open. 2025 Apr 19;7(7):907-912. doi: 10.1016/j.cjco.2025.03.027. eCollection 2025 Jul.
Data on the inducibility of atrial fibrillation (AF) following supraventricular tachycardia (SVT) ablation in patients without prior history of AF are limited. This study aims to identify features associated with inducible AF and the subsequent development of clinical AF in patients who undergo SVT ablation.
This prospective study enrolled patients who underwent electrophysiology study and SVT ablation. AF inducibility testing post ablation utilized decremental atrial burst pacing, employing the same protocol that previously had been demonstrated to have clinical significance following pulmonary vein isolation. AF was assessed clinically as well as through 12-lead electrocardiogram recordings and ambulatory Holter recordings.
A total of 152 patients who underwent an SVT ablation were evaluated. The median age was 53 years (range: 18-90); 87 patients were female (57.2%). Atrioventricular nodal reentrant tachycardia was diagnosed in 112 of the patients (73.6%), and 40 patients (26.3%) exhibited arrhythmias related to an accessory pathway. AF was induced in 31 patients (20.4%) during the induction protocol. Among patients with inducible AF, 79% spontaneously converted to sinus rhythm, and the rest were managed with cardioversion. During a median follow-up period of 514 ± 287 days, 6 patients (3.9%) developed clinical AF. Inducible AF at the time of the SVT procedure was associated with the development of clinical AF (odds ratio = 8.81, 95% confidence interval 1.53-50.63; = 0.01).
A significant proportion of patients undergoing SVT ablation have inducible AF, but only a few have clinical AF in the first 2 years of follow-up. Inducible AF after SVT ablation predicts future AF.
在无房颤病史的患者中,室上性心动过速(SVT)消融术后房颤(AF)的可诱导性数据有限。本研究旨在确定接受SVT消融的患者中与可诱导性房颤及随后临床房颤发生相关的特征。
这项前瞻性研究纳入了接受电生理检查和SVT消融的患者。消融术后房颤可诱导性测试采用递减心房猝发起搏,使用先前已证明在肺静脉隔离后具有临床意义的相同方案。通过临床评估以及12导联心电图记录和动态心电图监测来评估房颤。
总共对152例接受SVT消融的患者进行了评估。中位年龄为53岁(范围:18 - 90岁);87例患者为女性(57.2%)。112例患者(73.6%)被诊断为房室结折返性心动过速,40例患者(26.3%)表现出与旁路相关的心律失常。在诱导方案期间,31例患者(20.4%)诱发了房颤。在可诱导性房颤患者中,79%自发转为窦性心律,其余患者接受了心脏复律治疗。在中位随访期514±287天期间,6例患者(3.9%)发生了临床房颤。SVT手术时可诱导性房颤与临床房颤的发生相关(比值比 = 8.81,95%置信区间1.53 - 50.63;P = 0.01)。
接受SVT消融的患者中有相当一部分存在可诱导性房颤,但在随访的前两年中只有少数患者发生临床房颤。SVT消融后可诱导性房颤可预测未来房颤。