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一种用于乳腺癌放疗的新型自动皮肤闪光方法的性能评估

Performance evaluation of a new automated skin flash method for radiotherapy of breast cancer.

作者信息

Nykänen Topi, Raatikainen Ville, Kärnä Aarno, Koivumäki Tuomas

机构信息

Department of Medical Physics, Hospital Nova of Central Finland, Wellbeing Services County of Central Finland, Jyväskylä, Finland.

Department of Physics, University of Jyväskylä (JYU), Survontie 9 C, 40014 Jyväskylä, Finland.

出版信息

Phys Imaging Radiat Oncol. 2025 Jul 10;35:100810. doi: 10.1016/j.phro.2025.100810. eCollection 2025 Jul.

DOI:10.1016/j.phro.2025.100810
PMID:40698312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12281543/
Abstract

In volumetric modulated arc therapy of breast cancer, an outer margin for the target is needed. This study evaluated the clinical and planning target volume coverage and surface dose using an automated skin flash method compared to the virtual bolus method. Body outline changes of 4, 8 and 12 mm were simulated in 20 breast cancer patients. Median and clinical target volume coverage and surface dose remained at 90.1 %, 98.7 % and 85.7 % or above with the automated skin flash method. The median results of automated skin flash method were close to virtual bolus method.

摘要

在乳腺癌容积调强弧形治疗中,需要为靶区设置外放边界。本研究将自动皮肤闪射法与虚拟组织等效物法进行比较,评估了临床靶区和计划靶区的覆盖情况以及表面剂量。在20例乳腺癌患者中模拟了4毫米、8毫米和12毫米的身体轮廓变化。使用自动皮肤闪射法时,临床靶区覆盖的中位数、临床靶区覆盖率和表面剂量分别保持在90.1%、98.7%和85.7%及以上。自动皮肤闪射法的中位数结果与虚拟组织等效物法相近。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8959/12281543/695bd8877518/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8959/12281543/695bd8877518/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8959/12281543/695bd8877518/gr1.jpg

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本文引用的文献

1
The current practice of volumetric modulated arc therapy for breast cancer in Europe - A survey by the EFOMP VMAT breast working group.
Phys Med. 2025 Aug;136:105028. doi: 10.1016/j.ejmp.2025.105028. Epub 2025 Jun 24.
2
Automatic skin flash optimization in breast and chestwall VMAT with static angle modulated ports: Effect of HU and flash margin size on plan quality and robustness.使用静态角度调制射野的乳房和胸壁容积调强弧形治疗中的自动皮肤闪光优化:HU值和闪光边缘大小对计划质量和稳健性的影响
J Appl Clin Med Phys. 2025 May;26(5):e70036. doi: 10.1002/acm2.70036. Epub 2025 Feb 21.
3
Intensity Modulated Therapy for Patients With Breast Cancer. Practical Guidelines and Tips for an Effective Treatment Planning Strategy.乳腺癌患者的调强治疗。有效治疗计划策略的实用指南与技巧
Adv Radiat Oncol. 2024 May 6;9(8):101535. doi: 10.1016/j.adro.2024.101535. eCollection 2024 Aug.
4
The robustness of VMAT radiotherapy for breast cancer with tissue deformations.VMAT 放疗治疗乳腺癌组织变形的稳健性。
Med Dosim. 2021;46(1):86-93. doi: 10.1016/j.meddos.2020.09.005. Epub 2020 Sep 29.
5
Secondary cancer risk after radiation therapy for breast cancer with different radiotherapy techniques.乳腺癌放疗后不同放疗技术的继发癌症风险。
Sci Rep. 2020 Jan 27;10(1):1220. doi: 10.1038/s41598-020-58134-z.
6
Breast deformation during the course of radiotherapy: The need for an additional outer margin.放疗过程中的乳房变形:需要额外的外部边界。
Phys Med. 2019 Sep;65:1-5. doi: 10.1016/j.ejmp.2019.07.021. Epub 2019 Aug 5.
7
Pseudo skin flash on VMAT in breast radiotherapy: Optimization of virtual bolus thickness and HU values.VMAT 治疗乳腺癌中的假性皮肤闪光:虚拟填充物厚度和 HU 值的优化。
Phys Med. 2019 Jul;63:56-62. doi: 10.1016/j.ejmp.2019.05.010. Epub 2019 May 29.
8
Optimal selection of optimization bolus thickness in planning of VMAT breast radiotherapy treatments.容积调强弧形放疗(VMAT)乳腺放射治疗计划中优化推注厚度的最佳选择。
Med Dosim. 2019;44(3):266-273. doi: 10.1016/j.meddos.2018.10.001. Epub 2018 Oct 30.
9
Dosimetric effects of anatomical deformations and positioning errors in VMAT breast radiotherapy.容积调强弧形放疗中乳房放疗时解剖变形和摆位误差的剂量学影响
J Appl Clin Med Phys. 2018 Sep;19(5):506-516. doi: 10.1002/acm2.12409. Epub 2018 Jul 5.
10
Safety and benefit of using a virtual bolus during treatment planning for breast cancer treated with arc therapy.在乳腺癌弧形治疗计划中使用虚拟剂量的安全性和益处。
J Appl Clin Med Phys. 2018 Sep;19(5):463-472. doi: 10.1002/acm2.12398. Epub 2018 Jun 30.