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[抗菌药物管理项目团队会议频率增加对基于消耗量的医院抗菌药物使用指标的影响]

[Impact of increased meeting frequency of the antimicrobial stewardship program team on indicators of the hospital use of antimicrobial agents based on consumption].

作者信息

Zas-García María Inmaculada, Fernández-Carreira José Manuel, González-Fernández Daniel, Castelo-Alvárez Elsa, Rubio-Sanz Jesús, Álvarez-Pérez Marcos, Blanco-Suárez Ana, Rodríguez-Prida Jorge, Rubio-Alfonso Tania

机构信息

Hospital de Jarrio, Asturias, España.

出版信息

Rev Esp Quimioter. 2025 Sep 15;38(5):401-411. doi: 10.37201/req/042.2025. Epub 2025 Jul 23.

Abstract

OBJECTIVES

To analyze how the increased frequency of meetings held by the Antimicrobial Stewardship Program (PROA) groupduring which non-mandatory, supportive prescription audits were conductedimpacted antimicrobial use, using hospital antimicrobial consumption-based indicators. To compare these results with those of other centers of similar complexity.

MATERIALS AND METHODS

A retrospective cohort study comparing antimicrobial use through hospital antimicrobial consumption-based indicators in 2023 (the first year the PROA team met twice per week) with 2022 (the last year the PROA team met once per week). The comparison with other centers was carried out using the antimicrobial hospital consumption platform of the Pharmaceutical Care Group for Infectious Diseases of the Spanish Society of Hospital Pharmacy.

RESULTS

In 2023 compared to 2022, improvements were observed in 7 out of the 13 indicators: overall consumption of systemic antifungals, carbapenem consumption, metronidazole/piperacillin-tazobactam + carbapenem ratio, fosfomycin consumption, anti-MSSA/anti-MRSA agent ratio, amoxicillin-clavulanate/piperacillin-tazobactam ratio, and fluconazole/echinocandin ratio. In 2023, our hospital ranked above the 50th percentile in 7 out of the 13 indicators.

CONCLUSIONS

The increased frequency of PROA team meetings may be associated with partial improvements in antimicrobial use, according to hospital antimicrobial consumption-based indicators.

摘要

目的

使用基于医院抗菌药物消耗的指标,分析抗菌药物管理计划(PROA)小组增加会议频率(期间进行非强制性的支持性处方审核)如何影响抗菌药物的使用。并将这些结果与其他复杂性相似的中心进行比较。

材料与方法

一项回顾性队列研究,通过基于医院抗菌药物消耗的指标,比较2023年(PROA团队每周开会两次的第一年)和2022年(PROA团队每周开会一次的最后一年)的抗菌药物使用情况。与其他中心的比较是使用西班牙医院药学协会传染病药物治疗组的抗菌药物医院消耗平台进行的。

结果

与2022年相比,2023年13项指标中有7项有所改善:全身性抗真菌药物的总体消耗量、碳青霉烯类药物消耗量、甲硝唑/哌拉西林-他唑巴坦+碳青霉烯类药物比例、磷霉素消耗量、抗甲氧西林敏感金黄色葡萄球菌/抗耐甲氧西林金黄色葡萄球菌药物比例、阿莫西林-克拉维酸/哌拉西林-他唑巴坦比例以及氟康唑/棘白菌素比例。2023年,我院在13项指标中的7项上排名高于第50百分位。

结论

根据基于医院抗菌药物消耗的指标,PROA团队会议频率的增加可能与抗菌药物使用的部分改善有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f78/12447296/ea2eab797c74/revespquimioter-38-401-g001.jpg

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