A comparison of benzo(a)pyrene metabolism by liver and lung microsomal enzymes from 3-methylcholanthrene-treated rhesus monkeys and rats. - Suppr | 超能文献

A comparison of benzo(a)pyrene metabolism by liver and lung microsomal enzymes from 3-methylcholanthrene-treated rhesus monkeys and rats.

作者信息

Hundley S G, Freudenthal R I

出版信息

Cancer Res. 1977 Sep;37(9):3120-5.

Abstract

摘要

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Understanding the linked kinetics of benzo(a)pyrene and 3-hydroxybenzo(a)pyrene biomarker of exposure using physiologically-based pharmacokinetic modelling in rats.利用大鼠生理相关药代动力学模型理解苯并(a)芘和 3-羟基苯并(a)芘生物标志物暴露的连锁动力学。

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