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Modulation of the binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity.

作者信息

Viviani A, Lutz W K

出版信息

Cancer Res. 1978 Dec;38(12):4640-4.

PMID:719642
Abstract
摘要

相似文献

1
Modulation of the binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity.通过选择性诱导微粒体和细胞核芳烃羟化酶活性对致癌物苯并(a)芘在体内与大鼠肝脏DNA结合的调节作用。
Cancer Res. 1978 Dec;38(12):4640-4.
2
Influence of inducers and inhibitors of mixed-function oxidasts on benzo(a)pyrene binding to the DNA of rat liver nuclei.混合功能氧化酶诱导剂和抑制剂对苯并(a)芘与大鼠肝细胞核DNA结合的影响。
Cancer Res. 1977 May;37(5):1443-9.
3
Modulation of the in vivo covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity.通过选择性诱导微粒体和细胞核芳烃羟化酶活性来调节致癌物苯并(a)芘与大鼠肝脏DNA的体内共价结合。
Arch Toxicol Suppl. 1979(2):285-8. doi: 10.1007/978-3-642-67265-1_25.
4
Binding of metabolically activated benzo(a)pyrene to nuclear macromolecules.代谢活化的苯并(a)芘与核大分子的结合。
Cancer Res. 1976 Oct;36(10):3647-53.
5
Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.微粒体和细胞核芳烃单加氧酶、环氧化物水解酶以及细胞质谷胱甘肽S-环氧化物转移酶的特定诱导对致癌物苯并(a)芘在体内与大鼠肝脏DNA共价结合的影响。
J Cancer Res Clin Oncol. 1980;98(2):139-52. doi: 10.1007/BF00405958.
6
Time course of the induction of aryl hydrocarbon hydroxylase in rat liver nuclei and microsomes by phenobarbital, 3-methylcholanthrene, 2,3,7,8-tetrachloro-dibenzo-p-dioxin, dieldrin and other inducers.苯巴比妥、3-甲基胆蒽、2,3,7,8-四氯二苯并对二恶英、狄氏剂及其他诱导剂对大鼠肝细胞核和微粒体中芳烃羟化酶诱导作用的时间进程。
Biochem Pharmacol. 1978;27(17):2103-8. doi: 10.1016/0006-2952(78)90280-0.
7
A comparison of benzo(a)pyrene metabolism by liver and lung microsomal enzymes from 3-methylcholanthrene-treated rhesus monkeys and rats.
Cancer Res. 1977 Sep;37(9):3120-5.
8
Metabolic activation of aromatic hydrocarbons in purified rat liver nuclei: induction of enzyme activities and binding to DNA with and without monooxygenase-catalyzed formation of active oxygen.纯化大鼠肝细胞核中芳烃的代谢激活:酶活性的诱导以及在有无单加氧酶催化活性氧形成情况下与DNA的结合。
Proc Natl Acad Sci U S A. 1976 Feb;73(2):457-61. doi: 10.1073/pnas.73.2.457.
9
Kinetic analysis of the metabolism of benzo(a)pyrene to phenols, dihydrodiols, and quinones by high-pressure chromatography compared to analysis by aryl hydrocarbon hydroxylase assay, and the effect of enzyme induction.通过高压色谱法对苯并(a)芘代谢为酚类、二氢二醇和醌类的动力学分析与通过芳烃羟化酶测定法的分析比较,以及酶诱导的影响。
Cancer Res. 1975 Dec;35(12):3642-50.
10
The role of microsomes and nuclear envelope in the metabolic activation of benzo(a)pyrene leading to binding with nuclear macromolecules.微粒体和核膜在苯并(a)芘代谢活化导致与核大分子结合中的作用。
Cancer Res. 1977 Sep;37(9):3427-33.

引用本文的文献

1
Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.微粒体和细胞核芳烃单加氧酶、环氧化物水解酶以及细胞质谷胱甘肽S-环氧化物转移酶的特定诱导对致癌物苯并(a)芘在体内与大鼠肝脏DNA共价结合的影响。
J Cancer Res Clin Oncol. 1980;98(2):139-52. doi: 10.1007/BF00405958.
2
Interaction of estrone and estradiol with DNA and protein of liver and kidney in rat and hamster in vivo and in vitro.雌酮和雌二醇在大鼠和仓鼠体内及体外与肝脏和肾脏的DNA和蛋白质的相互作用。
Arch Toxicol. 1984 Jul;55(2):97-103. doi: 10.1007/BF00346046.
3
In vitro metabolism and in vivo binding of benzo(a)pyrene in the California killifish (Fundulus parvipinnis) and speckled sanddab (Citharicthys stigmaeous).
加州鳉鱼(Fundulus parvipinnis)和斑点沙鲽(Citharicthys stigmaeous)中苯并(a)芘的体外代谢及体内结合
Arch Environ Contam Toxicol. 1986 May;15(3):251-6. doi: 10.1007/BF01061101.