Uzun Oguz, Adıguzel Gundogdu Busra, Sullu Yurdanur, Topcu Erturk Kader, Kement Sümeyye, Selen Ala Cıtlak Fatma
Ondokuz Mayis University, Faculty of Medicine, Department of Pulmonary Medicine, Samsun, Turkey.
Ondokuz Mayis University, Faculty of Medicine, Deparment of Pulmonary Medicine, Samsun, Turkey.
Sarcoidosis Vasc Diffuse Lung Dis. 2025 Jun 25;42(2):15884. doi: 10.36141/svdld.v42i2.15884.
The aims of this study are (1) to investigate hypersensitivity pneumonitis (HP) related publications from Türkiye, (2) to discuss features of HP concerning our case series, and (3) to evaluate our patients in terms of diagnostic confidence according to guidelines.
We conducted a comprehensive review of the literature to analyse cumulated data about HP publications originating from Türkiye. HP cases diagnosed and followed in last 5 year in our hospital were also evaluated.
There are 34 Türkiye-originated HP-related publication. 13 articles were of pediatric origin and 19 of the articles included adult patients. Bird fancier's disease was the most frequent etiology of HP. A total of 138 patients were included in this study. 107 (77.5%) patients were female and 31 (22.5%) were male. A definite diagnosis has been made to 45 (33%) patients according to the ATS guideline and to 94 (68%) patients according to the ACCP guideline. 85 (62%) of the patients were in non-fibrotic form while 53 (38%) were in the fibrotic form. The most frequent etiology of our patient group was barn located under the houses in 58 (42%) patients.
Barns under the houses in rural areas and moldy houses in urban areas are two main etiology of HP in our region. The presence of chronic form mostly in our patient group shows HP can not be diagnosed at an early stage. We propose chronic forms to classify as "chronic inflammatory" and "chronic fibrotic". Classifying patients according to two new HP guidelines results in a very high "definite diagnosis" according to ACCP compared to ATS.
本研究的目的是：（1）调查来自土耳其的与过敏性肺炎（HP）相关的出版物；（2）结合我们的病例系列讨论HP的特征；（3）根据指南评估我们患者的诊断可信度。
我们对文献进行了全面回顾，以分析源自土耳其的关于HP出版物的累积数据。我们还评估了我院过去5年诊断和随访的HP病例。
有34篇源自土耳其的与HP相关的出版物。13篇文章是关于儿科病例，19篇文章包括成年患者。养鸟人病是HP最常见的病因。本研究共纳入138例患者。107例（77.5%）为女性，31例（22.5%）为男性。根据美国胸科学会（ATS）指南，45例（33%）患者得到明确诊断；根据美国胸科医师学会（ACCP）指南，94例（68%）患者得到明确诊断。85例（62%）患者为非纤维化形式，53例（38%）为纤维化形式。我们患者组最常见的病因是房屋下方的谷仓，共58例（42%）。
农村地区房屋下方的谷仓和城市地区发霉的房屋是我们地区HP的两个主要病因。我们患者组中慢性形式的存在表明HP无法在早期被诊断。我们建议将慢性形式分为“慢性炎症性”和“慢性纤维化性”。根据两项新的HP指南对患者进行分类，与ATS相比，ACCP的“明确诊断”率非常高。
