Shams Eddin Marwan, El Hajj Hussein, Zayyat Ramez, Lee Gayeon
Department of Systems Engineering and Operations Research, George Mason University, Fairfax, VA 22030, USA.
Department of Information Systems and Analytics, Santa Clara University, Santa Clara, CA 95053, USA.
Epidemiologia (Basel). 2025 Jul 8;6(3):33. doi: 10.3390/epidemiologia6030033.
: The COVID-19 pandemic highlighted the critical need for accurate predictive models to guide public health interventions and optimize healthcare resource allocation. This study evaluates how the complexity of compartmental infectious disease models influences their forecasting accuracy and utility for pandemic resource planning. : We analyzed a range of compartmental models, including simple susceptible-infected-recovered (SIR) models and more complex frameworks incorporating asymptomatic carriers and deaths. These models were calibrated and tested using real-world COVID-19 data from the United States to assess their performance in predicting symptomatic and asymptomatic infection counts, peak infection timing, and resource demands. Both adaptive models (updating parameters with real-time data) and non-adaptive models were evaluated. : Numerical results show that while more complex models capture detailed disease dynamics, simpler models often yield better forecast accuracy, especially during early pandemic stages or when predicting peak infection periods. Adaptive models provided the most accurate short-term forecasts but required substantial computational resources, making them less practical for long-term planning. Non-adaptive models produced stable long-term forecasts useful for strategic resource allocation, such as hospital bed and ICU planning. : Model selection should align with the pandemic stage and decision-making horizon. Simpler models are effective for rapid early-stage interventions, adaptive models excel in short-term operational forecasting, and non-adaptive models remain valuable for long-term resource planning. These findings can inform policymakers on selecting appropriate modeling approaches to improve pandemic response effectiveness.
:新冠疫情凸显了对准确预测模型的迫切需求,以指导公共卫生干预措施并优化医疗资源分配。本研究评估了传染病 compartmental 模型的复杂性如何影响其预测准确性以及在大流行资源规划中的效用。 :我们分析了一系列 compartmental 模型,包括简单的易感-感染-康复(SIR)模型以及包含无症状携带者和死亡情况的更复杂框架。这些模型使用来自美国的真实世界新冠数据进行校准和测试,以评估它们在预测有症状和无症状感染数量、感染高峰时间以及资源需求方面的表现。同时评估了自适应模型(使用实时数据更新参数)和非自适应模型。 :数值结果表明,虽然更复杂的模型能够捕捉详细的疾病动态,但较简单的模型通常具有更好的预测准确性,尤其是在疫情早期阶段或预测感染高峰期时。自适应模型提供了最准确的短期预测,但需要大量计算资源,这使得它们在长期规划中不太实用。非自适应模型产生的稳定长期预测对于战略资源分配(如医院床位和重症监护病房规划)很有用。 :模型选择应与疫情阶段和决策范围相匹配。较简单的模型对于快速的早期干预有效,自适应模型在短期运营预测方面表现出色,而非自适应模型在长期资源规划中仍然很有价值。这些发现可以为政策制定者在选择合适的建模方法以提高疫情应对有效性方面提供参考。
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