Lin Yi, Xu Minqi, Genis Helen, Andany Nisha, Chen Lina
Faculty of Arts & Science, University of Toronto, Toronto, ON M5S 1A1, Canada.
Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON K7L 2V7, Canada.
Reports (MDPI). 2025 Jul 17;8(3):111. doi: 10.3390/reports8030111.
Disseminated nocardiosis is a rare, life-threatening infection, often misdiagnosed due to its resemblance to other conditions. We report a case of disseminated nocardiosis in a 62-year-old post-renal transplant patient presenting with pulmonary, hepatic, and pancreatic lesions. Despite multiple negative bacterial cultures, a histopathological examination of the liver revealed necrotizing granulomas with filamentous microorganisms, ultimately identified as . This case highlights diagnostic challenges and the importance of integrating microbiological, pathological, and radiographical findings to manage and diagnose disseminated nocardiosis infections in immunocompromised individuals.
播散性诺卡菌病是一种罕见的、危及生命的感染,常因与其他病症相似而被误诊。我们报告一例62岁肾移植术后患者发生播散性诺卡菌病,表现为肺部、肝脏和胰腺病变。尽管多次细菌培养结果为阴性,但肝脏组织病理学检查发现坏死性肉芽肿伴丝状微生物,最终鉴定为…… 该病例突出了诊断方面的挑战,以及整合微生物学、病理学和影像学检查结果对于管理和诊断免疫功能低下个体播散性诺卡菌病感染的重要性。