Manjavong Manchumad, Limpawattana Panita, Chindaprasirt Jarin, Wareechai Poonchana
Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
National Health Security Office, Bangkok 10210, Thailand.
Geriatrics (Basel). 2025 Jul 1;10(4):88. doi: 10.3390/geriatrics10040088.
Delirium frequently manifests in hospitalized geriatric patients and is associated with negative health outcomes. Available large-scale data regarding its prevalence rate and impact on older Thai patients are limited. This study aimed to analyze trends in the prevalence rate, its consequences, and the factors contributing to death at discharge among this population.
A retrospective study of inpatients over the age of 60 who received a diagnosis of delirium was conducted, utilizing inpatient medical expense documentation for the fiscal years 2019-2023. The identification of delirium was conducted by the National Health Security Office using the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Thai Modification (ICD-10-TM) code F05.
The 5-year prevalence rate and mortality rate of delirium were 215.1 and 18.7/100,000 population, respectively, and tended to rise over the studied periods. The average hospitalization was 10 days, and the average healthcare expenditure was about 1470 USD/visit. Respiratory disease emerged as the most common primary diagnosis in delirious patients (23.5%). Factors associated with mortality were individuals aged >80 years when juxtaposed with the cohort aged 61-70 years (adjusted odds ratio [AOD] 1.07), being female (AOR 1.13), and a primary diagnosis of respiratory disease (AOR 2.72), cardiovascular disease (AOR 1.68), musculoskeletal disease (AOR 0.61), systemic infection/septicemia (AOR 2.08); or malignancy (AOR 2.97).
There was an upward trend in rates of both prevalence and mortality associated with delirium among hospitalized geriatric patients. Advancing age, gender, and particular primary diagnoses were associated with mortality at hospital discharge.
谵妄在老年住院患者中经常出现，并与不良健康后果相关。关于其患病率及对泰国老年患者影响的现有大规模数据有限。本研究旨在分析该人群的患病率趋势、其后果以及出院时导致死亡的因素。
利用2019 - 2023财年的住院医疗费用记录，对60岁以上被诊断为谵妄的住院患者进行回顾性研究。谵妄的识别由国家健康保险办公室使用《疾病和相关健康问题国际统计分类》第10次修订版泰国修改版（ICD - 10 - TM）编码F05进行。
谵妄的5年患病率和死亡率分别为215.1/10万人口和18.7/10万人口，且在研究期间呈上升趋势。平均住院时间为10天，平均医疗费用约为每次就诊1470美元。呼吸系统疾病是谵妄患者中最常见的主要诊断（23.5%）。与死亡率相关的因素包括与61 - 70岁队列相比年龄大于80岁的个体（调整优势比[AOD]为1.07）、女性（AOR为1.13）以及主要诊断为呼吸系统疾病（AOR为2.72）、心血管疾病（AOR为1.68）、肌肉骨骼疾病（AOR为0.61）、全身感染/败血症（AOR为2.08）或恶性肿瘤（AOR为2.97）。
老年住院患者中与谵妄相关的患病率和死亡率均呈上升趋势。年龄增长、性别和特定的主要诊断与出院时的死亡率相关。
