Akkan Jan, Bagheri Mahsa, Mezger Sophia, Fuchs Paul Christian, von Kohout Maria, Heitzmann Wolfram, Lefering Rolf, Schiefer Jennifer Lynn
Department of Plastic, Reconstructive, Hand and Burn Surgery, Hospital Cologne Merheim, University of Witten-Herdecke, 51109 Cologne, Germany.
Department of Plastic and Aesthetic Surgery, Emil von Behring Hospital, 14165 Berlin, Germany.
Eur Burn J. 2025 Jul 11;6(3):41. doi: 10.3390/ebj6030041.
Superficial partial thickness burns generally do not require surgical intervention and are managed with specialized wound dressings. Mepilex Ag is commonly used and often represents the standard of care. This study evaluated the clinical performance of pure silk compared to Mepilex Ag.
A prospective, single-center intraindividual study was conducted on adult patients with superficial partial thickness burns. Each burn wound was divided, treating one half with pure silk and the other with Mepilex Ag. Clinical parameters including wound closure time, pain levels, and scar quality at 3-month follow-up were analyzed.
Twenty-four patients were included (mean TBSA: 5.8%). Mepilex Ag showed a trend towards a shorter wound closure time (10.5 vs. 11.5 days; = 0.223). Pain scores remained below 4/10 for both dressings throughout treatment. However, Mepilex Ag demonstrated significantly lower pain on day one (3.5 vs. 2.77; = 0.039) and day two (2.91 vs. 2.27; = 0.041). Scar quality after 3 months was similar.
Both dressings proved to be effective treatment options. Pure silk required fewer resources, showed high clinical practicality, and demonstrated a similar performance to Mepilex Ag in key clinical parameters, making it an interesting option for other clinics and our standard of care.
浅Ⅱ度烧伤一般不需要手术干预，采用专门的伤口敷料进行处理。美皮康银敷料是常用的，且常代表护理标准。本研究评估了纯丝绸敷料与美皮康银敷料相比的临床性能。
对成年浅Ⅱ度烧伤患者进行了一项前瞻性、单中心个体内研究。每个烧伤创面被分为两半，一半用纯丝绸敷料治疗，另一半用美皮康银敷料治疗。分析了包括伤口愈合时间、疼痛程度和3个月随访时的瘢痕质量等临床参数。
纳入24例患者（平均烧伤总面积：5.8%）。美皮康银敷料显示出伤口愈合时间有缩短的趋势（10.5天对11.5天；P = 0.223）。在整个治疗过程中，两种敷料的疼痛评分均保持在4/10以下。然而，美皮康银敷料在第1天（3.5对2.77；P = 0.039）和第2天（2.91对2.27；P = 0.041）的疼痛明显更低。3个月后的瘢痕质量相似。
两种敷料均被证明是有效的治疗选择。纯丝绸敷料所需资源更少，具有较高的临床实用性，并且在关键临床参数方面表现与美皮康银敷料相似，使其成为其他诊所感兴趣的选择以及我们的护理标准。
