使用染发剂后发生的严重再生障碍性贫血：两例报告并文献复习
Severe aplastic anaemia following the use of hair dye: report of two cases and review of literature.
作者信息
Hopkins J E, Manoharan A
出版信息
Postgrad Med J. 1985 Nov;61(721):1003-5. doi: 10.1136/pgmj.61.721.1003.
We describe two female patients aged 31 and 62 y who developed severe aplastic anaemia following the use of hair dye containing para-toluenediamine. One received a bone marrow transplant but died after developing graft versus host disease and severe opportunistic infection. The second responded to treatment with methylprednisolone, oxymetholone and antithymocyte globulin and 3 y later she has a normal blood count apart from mild thrombocytopenia. In this paper we also review previously described case reports of aplastic anaemia apparently associated with the use of hair dye.
我们描述了两名分别为31岁和62岁的女性患者，她们在使用含有对苯二胺的染发剂后患上了严重再生障碍性贫血。其中一名接受了骨髓移植，但在发生移植物抗宿主病和严重机会性感染后死亡。第二名患者对甲泼尼龙、羟甲烯龙和抗胸腺细胞球蛋白治疗有反应，3年后除轻度血小板减少外，血细胞计数正常。在本文中，我们还回顾了先前描述的明显与使用染发剂相关的再生障碍性贫血病例报告。
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