Peiker G, Siegert C, Glöckner R, Völkner E, Traeger A
Pharmazie. 1985 Sep;40(9):645-7.
The treatment of the mentioned forms of hypertension with propranolol during pregnancy either as monotherapy or in combination with dihydralazine and after careful exclusion of the contraindications described represents a further effective therapy. In the control examinations during pregnancy carried out in close cooperation between obstetrician and internist no detrimental side effects could be established for both mother and child. No significant changes of absorption, distribution and elimination of propranolol in pregnant women with hypertension in comparison with normotensive nonpregnant women were found as follows from the pharmacokinetic parameters shown.
在孕期对上述类型的高血压使用普萘洛尔进行治疗，无论是单一疗法还是与双肼屈嗪联合使用，并且在仔细排除所述禁忌证之后，是另一种有效的治疗方法。在产科医生和内科医生密切合作进行的孕期对照检查中，未发现对母婴有有害的副作用。从所示的药代动力学参数可以看出，与血压正常的非孕妇相比，高血压孕妇体内普萘洛尔的吸收、分布和消除没有显著变化。
