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[探索疼痛、年龄、性别、生活质量、功能能力和睡眠之间的联系:社区药房的一项分析]

[Exploring the Connection Between Pain, Age, Sex, Quality of Life, Functional Capacity, And Sleep: An Analysis in Community Pharmacy].

作者信息

Reyes Estévez D, González Rodríguez A, Morcuende Campos A, Córcoles Ferrándiz M E, Merencio Naudin E

机构信息

Farmacéutico comunitario en Granadilla de Abona (Tenerife), Farmacia La Comunitaria Dr. Antonio Villfaina Barroso España.

Farmacéutica comunitaria en Madrid, Farmacia Congosto Lcda. Ángela González Hernández España.

出版信息

Farm Comunitarios. 2025 Jul 8;17(3):89-119. doi: 10.33620/FC.2173-9218.(2025).24. eCollection 2025 Jul 15.


DOI:10.33620/FC.2173-9218.(2025).24
PMID:40703485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12282470/
Abstract

INTRODUCTION: Pain has a significant impact on quality of life. Personalized care emerges as a key strategy in pain management. Objectives: To identify the characteristics of patients with acute or chronic pain who visit the community pharmacy (CP) and to analyze the relationships between these characteristics in order to support future research. MATERIAL AND METHODS: A descriptive, observational, cross-sectional, multicenter study was conducted in patients experiencing pain who attended community pharmacies (CPs). The study took place from October 14 to 27, 2019, in 47 CPs across Spain. The variables analyzed included: pain intensity (VAS), type of pain based on duration and diagnosis, type of medication, quality of life (EuroQoL-5D questionnaire), functional capacity (Karnofsky Performance Status), sleep quality (Insomnia Severity Index - ISI), and satisfaction with treatment. RESULTS: A total of 403 participants were included: 28% were men and 72% women; 39% were over 70 years old, 45% between 40-69 years, and 16% between 18-39 years. Acute pain was reported by 25% of subjects, and chronic pain by 75%; 90% had non-oncological pain. The mean values observed were: VAS 6.1; EuroQoL 8.3; Karnofsky 78.1; and ISI 9.7. The correlational analysis between VAS, EuroQoL-5D, Karnofsky, and ISI, performed using Spearman's correlation coefficient (SC), showed statistically significant correlations: VAS and EuroQoL (SC=0.47; p<0.001), VAS and EuroQoL pain dimension (SC=0.52; p<0.001), VAS and ISI (SC=0.33; p<0.001), and a negative correlation between VAS and Karnofsky (SC=-0.33; p<0.001). CONCLUSIONS: Correlations were identified between age and quality of life, as well as between sex and age with functional capacity. Finally, an association was observed between pain intensity (measured using the VAS scale) and indicators of quality of life, sleep quality, and functional capacity.

摘要

引言:疼痛对生活质量有重大影响。个性化护理已成为疼痛管理的关键策略。目的:确定前往社区药房(CP)的急性或慢性疼痛患者的特征,并分析这些特征之间的关系,以支持未来的研究。 材料与方法:对前往社区药房(CP)的疼痛患者进行了一项描述性、观察性、横断面、多中心研究。该研究于2019年10月14日至27日在西班牙的47家社区药房进行。分析的变量包括:疼痛强度(视觉模拟评分法[VAS])、基于持续时间和诊断的疼痛类型、药物类型、生活质量(欧洲五维健康量表问卷)、功能能力(卡氏功能状态评分)、睡眠质量(失眠严重程度指数[ISI])以及对治疗的满意度。 结果:共纳入403名参与者:男性占28%,女性占72%;39%的参与者年龄超过70岁,45%的参与者年龄在40至69岁之间,16%的参与者年龄在18至39岁之间。25%的受试者报告有急性疼痛,75%的受试者报告有慢性疼痛;90%的患者患有非肿瘤性疼痛。观察到的平均值为:VAS为6.1;欧洲五维健康量表评分为8.3;卡氏功能状态评分为78.1;ISI为9.7。使用斯皮尔曼相关系数(SC)对VAS、欧洲五维健康量表-5D、卡氏功能状态评分和ISI进行的相关性分析显示,存在统计学显著相关性:VAS与欧洲五维健康量表(SC = 0.47;p < 0.001)、VAS与欧洲五维健康量表疼痛维度(SC = 0.52;p < 0.001)、VAS与ISI(SC = 0.33;p < 0.001),以及VAS与卡氏功能状态评分之间呈负相关(SC = -0.33;p < 0.001)。 结论:确定了年龄与生活质量之间以及性别和年龄与功能能力之间的相关性。最后,观察到疼痛强度(使用VAS量表测量)与生活质量、睡眠质量和功能能力指标之间存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/b72beca847f2/FC17-03-09_gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/9419faa70cd9/FC17-03-09_gf01.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/05653260ab1a/FC17-03-09_gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/b72beca847f2/FC17-03-09_gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/9419faa70cd9/FC17-03-09_gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/bc6ce6c1afc6/FC17-03-09_gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/05653260ab1a/FC17-03-09_gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf1/12282470/b72beca847f2/FC17-03-09_gf04.jpg

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本文引用的文献

[1]
Identifying patient subgroups in the heterogeneous chronic pain population using cluster analysis.

J Pain. 2025-3

[2]
Prevalence and epidemiological characteristics of chronic pain in the Spanish population. Results from the pain barometer.

Eur J Pain. 2025-1

[3]
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Sci Rep. 2024-5-31

[4]
The Management of Chronic Pain: Re-Centring Person-Centred Care.

J Clin Med. 2023-11-7

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Rev Esp Salud Publica. 2023-9-6

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BMC Health Serv Res. 2023-5-25

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Eur J Pain. 2022-3

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Pain Manag. 2021-4

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