Bennun R D, Mulliken J B, Kaban L B, Murray J E
Plast Reconstr Surg. 1985 Dec;76(6):859-65.
An analysis of associated deformities in 74 patients with isolated microtia is reported. Microtia should be considered a microform of hemifacial microsomia because of similar (1) asymmetrical nature of the defects, (2) incidence and pattern of seventh nerve paresis, (3) correlation of the degree of seventh nerve weakness with grade of auricular deformity and not with the severity of mandibular hypoplasia, (4) right-sided preponderance, (5) incidence of associated cleft lip and palate, (6) male predilection, and (7) equivocal mode of inheritance. These clinical observations confirm the concept that microtia and hemifacial microsomia have the same etiopathogenesis which is not shared by mandibulofacial dysostosis.
本文报道了对74例孤立性小耳畸形患者相关畸形的分析。小耳畸形应被视为半侧颜面短小畸形的一种微小型,原因如下:(1) 缺陷具有相似的不对称性;(2) 第七神经麻痹的发生率和模式;(3) 第七神经麻痹程度与耳廓畸形程度相关,而非与下颌发育不全的严重程度相关;(4) 右侧优势;(5) 伴有唇腭裂的发生率;(6) 男性居多;(7) 遗传方式不明确。这些临床观察结果证实了小耳畸形和半侧颜面短小畸形具有相同的发病机制,而下颌面骨发育不全并不具备这一机制。