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唇腭裂与耳部畸形

Cleft Lip and/or Palate and Auricular Malformations.

作者信息

Suutarla Samuli, Rautio Jorma, Klockars Tuomas

出版信息

Cleft Palate Craniofac J. 2015 Jan;52(1):62-5. doi: 10.1597/13-069.

Abstract

OBJECTIVE

To study the relationship between cleft lip and/or palate and auricular malformations in Finnish patients with cleft.

DESIGN

Retrospective analysis of patients with an external ear malformation and either a cleft lip with or without a cleft palate (CL±P) or an isolated cleft palate (CP).

SETTING

Tertiary referral clinic.

PATIENTS

Review of hospital records of 100 patients from the register of 8200 patients with cleft in the Cleft and Craniofacial Centre at the Helsinki University Central Hospital.

MAIN OUTCOME MEASURES

Proportions of variable auricular malformations among CL±P and CP patients.

RESULTS

Microtia is the most common auricular malformation among patients with cleft and is almost equally prevalent with both CL±P and CP. The prevalence of microtia increases as the severity of CL±P increases. The combination of microtia and CL±P or CP is frequently found with both oculo-auriculo-vertebral spectrum and Treacher Collins syndrome.

CONCLUSIONS

Microtia seems to be the most common auricular malformation among patients with cleft. The prevalence of microtia seems to increase as the severity of CL±P increases, whereas in isolated CP microtia seems to occur independently.

摘要

目的

研究芬兰腭裂患者唇裂和/或腭裂与耳部畸形之间的关系。

设计

对伴有外耳道畸形以及唇裂伴或不伴腭裂(CL±P)或孤立性腭裂(CP)的患者进行回顾性分析。

地点

三级转诊诊所。

患者

回顾赫尔辛基大学中心医院腭裂与颅面中心8200例腭裂患者登记册中的100例患者的医院记录。

主要观察指标

CL±P和CP患者中各种耳部畸形的比例。

结果

小耳畸形是腭裂患者中最常见的耳部畸形,在CL±P和CP患者中几乎同样普遍。随着CL±P严重程度的增加,小耳畸形的患病率也增加。小耳畸形与CL±P或CP的组合常见于眼耳脊椎综合征和特雷彻·柯林斯综合征。

结论

小耳畸形似乎是腭裂患者中最常见的耳部畸形。随着CL±P严重程度的增加,小耳畸形的患病率似乎增加,而在孤立性CP中,小耳畸形似乎独立发生。

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