2022 - 2023年贝宁裂谷热病毒和克里米亚 - 刚果出血热病毒血清阳性率
Seroprevalence of Rift Valley and Crimean-Congo Hemorrhagic Fever Viruses, Benin, 2022-2023.
作者信息
Olk Nadine, Yadouleton Anges, Quenum Olga, Sohou Stephane, Goundote Aime, Rodrigue Grace Aho Glele, Guezo-Mevo Blaise, Bedie Sonia, Nagel Michael, Emmerich Petra, Hounkpatin Benjamin, Drexler Jan Felix
出版信息
Emerg Infect Dis. 2025 Aug;31(8):1662-1665. doi: 10.3201/eid3108.250020.
We screened 650 febrile patients from Benin for Rift Valley fever and Crimean-Congo hemorrhagic fever viruses during 2022-2023. None were positive by reverse transcription PCR; 1.1% and 0.3%, respectively, had virus-specific IgG. False-positive results from malaria-associated antibodies likely reacting with histidine-tagged viral antigens mandate careful validation of serologic tests in malaria-endemic regions.
2022年至2023年期间，我们对来自贝宁的650名发热患者进行了裂谷热病毒和克里米亚-刚果出血热病毒筛查。逆转录聚合酶链反应检测结果均为阴性；分别有1.1%和0.3%的患者有病毒特异性IgG。疟疾相关抗体可能与组氨酸标记的病毒抗原发生反应导致假阳性结果，这就要求在疟疾流行地区对血清学检测进行仔细验证。
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