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即刻种植与牙槽嵴保存后的骨稳定性:一项15年的回顾性临床研究。

Bone Stability After Immediate Implants and Alveolar Ridge Preservation: A 15-Year Retrospective Clinical Study.

作者信息

Angelis Nicola De, Pesce Paolo, Yumang Catherine, Baldi Domenico, Menini Maria

机构信息

Department of Surgical Sciences and Integrated Diagnostics, Unit of Implant and Prosthodontics, University of Genoa, 16126 Genova, Italy.

Dental Department, University Technology MARA, Sungai Buloh 47000, Malaysia.

出版信息

Dent J (Basel). 2025 Jul 2;13(7):299. doi: 10.3390/dj13070299.

DOI:10.3390/dj13070299
PMID:40710144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12293914/
Abstract

In modern dentistry, alveolar socket preservation after tooth extraction plays a critical role in maintaining the alveolar ridge for future dental implants. This retrospective clinical study evaluated bone-level changes 15 years after immediate implant placement, coupled with alveolar ridge preservation. Fifty non-smoking patients aged 25 to 75 (30 males and 20 females) who underwent single-implant rehabilitation in both anterior and posterior regions of the upper and lower jaws were included. The study examined bone levels and implant survival over time, using standardized intraoral radiographs at 1, 5, and 15 years post-loading. Implants were placed immediately after atraumatic extraction, and the residual gap was grafted with bovine hydroxyapatite and covered with a collagen membrane. The primary outcome was bone-level stability, while secondary outcomes included implant failure. No temporary crowns or removable dentures were provided during healing. Radiographs were digitized for detailed analysis. The results for 50 patients with immediate implant placement showed that bone-resorption levels were significantly higher in the upper jaw than in the lower jaw. Posterior implants exhibited greater bone loss than anterior implants, particularly at 1 year and 15 years, while no implant failures occurred.

摘要

在现代牙科中,拔牙后牙槽窝保存对于维持牙槽嵴以用于未来的牙种植体起着关键作用。这项回顾性临床研究评估了即刻种植并结合牙槽嵴保存15年后的骨水平变化。纳入了50名年龄在25至75岁之间的非吸烟患者(30名男性和20名女性),他们在上颌和下颌的前部和后部区域接受了单颗种植修复。该研究使用加载后1年、5年和15年的标准化口腔内X光片,随时间检查骨水平和种植体存活率。在无创拔牙后立即植入种植体,剩余间隙用牛羟基磷灰石移植并覆盖胶原膜。主要结果是骨水平稳定性,次要结果包括种植体失败。愈合期间未提供临时冠或可摘义齿。X光片数字化以进行详细分析。50例即刻种植患者的结果显示,上颌骨吸收水平显著高于下颌骨。后部种植体比前部种植体表现出更大的骨丢失,尤其是在1年和15年时,且未发生种植体失败。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/4577cd321926/dentistry-13-00299-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/1d5a2e477536/dentistry-13-00299-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/e3628530cb75/dentistry-13-00299-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/09b8ffe3a511/dentistry-13-00299-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/4577cd321926/dentistry-13-00299-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/1d5a2e477536/dentistry-13-00299-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/e3628530cb75/dentistry-13-00299-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/09b8ffe3a511/dentistry-13-00299-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd2/12293914/4577cd321926/dentistry-13-00299-g004.jpg

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本文引用的文献

1
A novel porcine dentin-derived bone graft material provides effective site stability for implant placement after tooth extraction: a randomized controlled clinical trial.一种新型猪牙本质衍生骨移植材料为拔牙后种植体植入提供了有效的位点稳定性:一项随机对照临床试验。
Clin Oral Investig. 2023 Jun;27(6):2899-2911. doi: 10.1007/s00784-023-04888-5. Epub 2023 Feb 24.
2
Bone dimensional changes after flapless immediate implant placement with and without bone grafting: Randomized clinical trial.不翻瓣即刻种植并同期植骨与未植骨后的骨维度变化:随机临床试验
Clin Implant Dent Relat Res. 2023 Apr;25(2):271-283. doi: 10.1111/cid.13178. Epub 2023 Jan 3.
3
An Analysis of Different Techniques Used to Seal Post-Extractive Sites-A Preliminary Report.
拔牙后创口封闭不同技术的分析——初步报告
Dent J (Basel). 2022 Oct 9;10(10):189. doi: 10.3390/dj10100189.
4
Minimal invasiveness in the alveolar ridge preservation, with or without concomitant implant placement.微创牙槽嵴保存术,伴或不伴同期种植体植入。
Periodontol 2000. 2023 Feb;91(1):65-88. doi: 10.1111/prd.12441. Epub 2022 Aug 1.
5
Comparison of Bone-Level and Tissue-Level Implants: A Pilot Study with a Histologic Analysis and a 4-Year Follow-up.骨水平种植体与软组织水平种植体的比较:一项组织学分析和 4 年随访的初步研究。
Int J Periodontics Restorative Dent. 2022 Jul-Aug;42(4):535-543. doi: 10.11607/prd.4990.
6
The Effect of an Alloplastic Bone Substitute and Enamel Matrix Derivative on the Preservation of Single Anterior Extraction Sockets: A Histologic Study in Humans.异体骨替代物和釉基质衍生物对单个前牙拔牙窝保存效果的影响:一项人体组织学研究。
Int J Periodontics Restorative Dent. 2022 May-Jun;42(3):361-368. doi: 10.11607/prd.4917.
7
Bone and Soft Tissue Modifications in Immediate Implants Versus Delayed Implants Inserted Following Alveolar Ridge Preservation: A Randomized Controlled Clinical Trial. Part I: Esthetic Outcomes.即刻种植与牙槽嵴保存后延期种植的骨与软组织改建:一项随机对照临床试验。第一部分:美学结果。
Int J Periodontics Restorative Dent. 2022 Mar-Apr;42(2):195-202. doi: 10.11607/prd.5565.
8
Immediate implant placement with or without socket grafting: A systematic review and meta-analysis.即刻种植并同期行植骨术与延期种植:系统评价和荟萃分析。
Clin Implant Dent Relat Res. 2022 Jun;24(3):339-351. doi: 10.1111/cid.13079. Epub 2022 Mar 21.
9
A 3-year prospective randomized clinical trial of alveolar bone crest response and clinical parameters through 1, 2, and 3 years of clinical function of implants placed 4 months after alveolar ridge preservation using two different allogeneic bone-grafting materials.一项为期 3 年的前瞻性随机临床试验,评估了使用两种不同同种异体骨移植材料进行牙槽嵴保存后 4 个月植入种植体的临床功能 1、2 和 3 年时牙槽嵴顶反应和临床参数。
Int J Implant Dent. 2022 Feb 1;8(1):5. doi: 10.1186/s40729-022-00402-w.
10
Randomized controlled clinical study comparing two types of two-piece dental implants supporting fixed restorations-Results at 8 years of loading.随机对照临床试验比较两种类型的两段式牙科种植体支持固定修复体-8 年负荷的结果。
Clin Oral Implants Res. 2022 Mar;33(3):333-341. doi: 10.1111/clr.13893. Epub 2022 Feb 3.