Suwa Uziel Ferreira, Simão Carla Letícia Gomes, Barbosa Ulysses Carvalho, Sousa Patrícia Moura, Araújo Cláudia Patrícia Mendes de, Martins Marilaine, Crainey James Lee
Laboratório de Ecologia de Doenças Transmissíveis na Amazônia, Instituto Leônidas e Maria Deane, Fundação Oswaldo Cruz Amazônia, Manaus 69057-070, Amazonas, Brazil.
Programa de Doutorado em Saúde Pública na Amazônia, Instituto Leônidas e Maria Deane, Manaus 69057-070, Amazonas, Brazil.
Trop Med Infect Dis. 2025 Jul 2;10(7):186. doi: 10.3390/tropicalmed10070186.
Mansonellosis is a chronic infectious tropical disease that affects hundreds of millions of people worldwide but is not currently targeted for control. In this study, we interviewed 320 residents from Sao Gabriel do Cachoeira (SGC) about their support for soil transmitted helminth (STH) and mansonellosis interventions. Our survey found no significant difference between community support for mansonellosis and STH disease treatment when comparing any equivalent treatment regimen or program, although support for STH treatments was always higher than for mansonellosis treatments. No significant differences were detected when comparing community members' willingness to participate in treatment programs and their willingness to allow family members to participate in an equivalent program. Our survey did, however, almost always find that significantly more community members were willing to participate in a proposed treatment program if the treatment regimen of that program was shorter than an otherwise equivalent regimen. Although significantly fewer people said they would participate in a curative four-week treatment course for mansonellosis than in a mansonellosis mass drug administration (MDA) program, significantly more community members said they would take a curative mansonellosis treatment course that lasted seven days or less than they would participate in any type of anthelminthic MDA proposed to them. The number of community members who said they would participate in any helminthic treatment program if they knew there was a ≥50% chance that they were infected was significantly higher than the number who said that they would without knowing the regional prevalence rate.
曼氏丝虫病是一种慢性传染性热带疾病，全球数亿人受其影响，但目前并未将其作为防治对象。在本研究中，我们采访了320名来自卡舒埃拉圣加布里埃尔（SGC）的居民，了解他们对土壤传播蠕虫（STH）和曼氏丝虫病干预措施的支持情况。我们的调查发现，在比较任何等效的治疗方案或项目时，社区对曼氏丝虫病和STH疾病治疗的支持没有显著差异，尽管对STH治疗的支持总是高于对曼氏丝虫病治疗的支持。在比较社区成员参与治疗项目的意愿和允许家庭成员参与等效项目的意愿时，未发现显著差异。然而，我们的调查几乎总是发现，如果某个项目的治疗方案比其他等效方案短，那么愿意参与该项目的社区成员明显更多。虽然表示愿意参加为期四周的曼氏丝虫病治疗疗程的人数明显少于参加曼氏丝虫病群体药物治疗（MDA）项目的人数，但表示愿意接受为期七天或更短时间的曼氏丝虫病治疗疗程的社区成员明显多于愿意参加向他们提议的任何类型驱虫MDA项目的人数。表示如果知道自己感染几率≥50%就会参加任何蠕虫治疗项目的社区成员数量，明显高于表示在不知道地区患病率的情况下会参加的人数。
