Halstead L S, Wiechers D O, Rossi C D
South Med J. 1985 Nov;78(11):1281-7.
We present the results of a survey on the late effects of poliomyelitis in 201 persons. The most common new problems were fatigue, weakness in previously affected and unaffected muscles, muscle pain, and joint pain. The median time from poliomyelitis to onset of new problems ranged from 30 to 40 years. Factors at onset of polio most strongly associated with development of these late effects of polio were (1) hospitalization (P less than 0.00001), (2) age greater than 10 years (P less than 0.00001), (3) ventilator use (P less than 0.0029), and (4) paralytic involvement of all four limbs (P less than 0.0240). The differential diagnosis of these new problems, implications for treatment, and areas for future research are discussed.
我们展示了一项针对201名脊髓灰质炎后遗症患者的调查结果。最常见的新问题包括疲劳、先前受累及未受累肌肉的无力、肌肉疼痛和关节疼痛。从脊髓灰质炎发病到出现新问题的中位时间为30至40年。脊髓灰质炎发病时与这些脊髓灰质炎后遗症发生最密切相关的因素为：（1）住院治疗（P<0.00001），（2）年龄大于10岁（P<0.00001），（3）使用呼吸机（P<0.0029），以及（4）四肢均有麻痹性受累（P<0.0240）。文中讨论了这些新问题的鉴别诊断、治疗意义及未来研究方向。
