Cowie R L, Langton M E, Escreet B C
S Afr Med J. 1985 Dec 7;68(12):879-80.
A group of 250 patients with new or enlarging apical lung lesions which were thought to be tuberculous, and who had positive tuberculin tests but negative sputum smears and cultures for Mycobacterium tuberculosis, were treated with an ultrashort (3-month), 4-drug (rifampicin, isoniazid, pyrazinamide and ethambutol) regimen. One patient developed bacteriologically positive pulmonary tuberculosis (PTB) during the treatment period and 35 others (14%) developed bacteriologically positive PTB after completing the drug regimen.
一组250例患者，其肺部新出现或增大的尖部病变被认为是结核性的，结核菌素试验呈阳性，但痰涂片和结核分枝杆菌培养均为阴性，接受了超短程（3个月）四联（利福平、异烟肼、吡嗪酰胺和乙胺丁醇）治疗方案。1例患者在治疗期间出现细菌学阳性的肺结核（PTB），另外35例（14%）在完成治疗方案后出现细菌学阳性的PTB。
