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微创与开放造口旁疝修补术:一项全面的系统评价和荟萃分析。

Minimally Invasive Versus Open Parastomal Hernia Repair: A Comprehensive Systematic Review and Meta-Analysis.

作者信息

Abdelsamad Ahmed, Mohammed Mohammed Khaled, Almoshantaf Mohamed Badr, Alrawi Aya, Fadl Ziad A, Tarek Ziad, Aboelmajd Nada Osama, Herzog Torsten, Gebauer Florian, Abdelsattar Nada K, Taha Taha Abd-Elsalam Ashraf

机构信息

Department of Surgery II, University of Witten - Herdecke, Witten, Germany.

Oncological Surgery Department, Section Head of Robotic Surgery, Knappschaft Vest- Hospital, Recklinghausen, Germany.

出版信息

World J Surg. 2025 Sep;49(9):2382-2398. doi: 10.1002/wjs.70013. Epub 2025 Jul 25.

Abstract

BACKGROUND

Parastomal hernia is a frequent and complex complication following stoma creation, often requiring surgical intervention. The optimal repair technique remains a subject of debate, with open and minimally invasive approaches each presenting distinct advantages and limitations. This meta-analysis systematically compares these techniques for parastomal hernia repair, evaluating key clinical outcomes including short- and long-term results.

METHODS

We performed a comprehensive systematic review and meta-analysis following PRISMA guidelines, searching the PubMed, Web of Science, Scopus, and Cochrane Library databases through October 2024. Studies were included if they involved adult patients undergoing parastomal hernia repair using open and minimally invasive techniques, and reported at least two relevant clinical outcomes. Data were analyzed using Review Manager 5.4. Risk ratios (RRs) and mean differences (MDs) were calculated, with heterogeneity assessed through p-values. A random-effects model was applied for analyses with substantial heterogeneity.

RESULTS

Minimally invasive approaches were associated with favorable outcomes compared to open surgery in several key parameters. Laparoscopic repair significantly reduced hospital stay by an average of 4 days compared to open techniques (p < 0.00001) and showed significantly lower complication rates, including surgical site infections (RR: 0.37- 0.63, p-values 0.02-0.03). Mortality was also significantly reduced in the laparoscopic group (RR: 0.18; p = 0.0009) while recurrence rates showed no significant difference between approaches. Robotic-assisted repair demonstrated a potential reduction in operative time (RR = 0.60, p = 0.007); however, this finding is based on a limited sample and should be interpreted with caution.

CONCLUSION

Laparoscopic repair of parastomal hernias provides significant advantages over open surgery including reduced morbidity, shorter hospital stays, and fewer complications. Although limited by sample size, robotic-assisted repair seems promising in reducing operative time and may offer added value in complex or recurrent cases; however, further research is needed to validate its cost-effectiveness and long-term outcomes. These findings support the preferential use of a minimally invasive approach in parastomal hernia repair whenever feasible while acknowledging that an individualized approach may still be necessary based on patient-specific factors and institutional resources.

摘要

背景

造口旁疝是造口术后常见且复杂的并发症,常需手术干预。最佳修复技术仍是一个有争议的话题,开放手术和微创手术各有其独特的优势和局限性。本荟萃分析系统地比较了这些造口旁疝修复技术,评估了包括短期和长期结果在内的关键临床结局。

方法

我们按照PRISMA指南进行了全面的系统评价和荟萃分析,检索了截至2024年10月的PubMed、Web of Science、Scopus和Cochrane图书馆数据库。纳入的研究需涉及使用开放手术和微创手术进行造口旁疝修复的成年患者,并报告至少两项相关临床结局。使用Review Manager 5.4对数据进行分析。计算风险比(RRs)和均值差(MDs),通过p值评估异质性。对于存在显著异质性的分析,应用随机效应模型。

结果

与开放手术相比,微创手术在几个关键参数方面具有更好的结局。与开放技术相比,腹腔镜修复显著缩短平均住院时间4天(p < 0.00001),且并发症发生率显著更低,包括手术部位感染(RR:0.37 - 0.63,p值0.02 - 0.03)。腹腔镜组的死亡率也显著降低(RR:0.18;p = 0.0009),而两种手术方式的复发率无显著差异。机器人辅助修复显示出手术时间可能缩短(RR = 0.60,p = 0.007);然而,这一发现基于有限的样本,应谨慎解读。

结论

造口旁疝的腹腔镜修复相对于开放手术具有显著优势,包括发病率降低、住院时间缩短和并发症减少。尽管受样本量限制,机器人辅助修复在缩短手术时间方面似乎很有前景,可能在复杂或复发病例中提供附加价值;然而,需要进一步研究来验证其成本效益和长期结局。这些发现支持在可行的情况下优先采用微创手术修复造口旁疝,同时认识到基于患者特定因素和机构资源,个体化方法可能仍然必要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace4/12435612/0e094381dacc/WJS-49-2382-g005.jpg

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