Ghazawy Nirvina Abdel Raouf, Radwan Ibrahim Taha, Gattan Hattan S, Alruhaili Mohammed H, Baz Mohamed M, AbdelFattah Eman Alaaeldin, Mashlawi Abadi M, Selim Abdelfattah
Department of Entomology, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Supplementary General Sciences Department, Faculty of Oral and Dental Medicine, Future University in Egypt, Cairo, 11835, Egypt.
Sci Rep. 2025 Jul 25;15(1):27076. doi: 10.1038/s41598-025-11550-5.
Hundreds of species of mosquitoes are reported to be capable of transmitting diseases to humans. As a result, mosquito control is essential worldwide, especially in locations with large concentrations of freshwater sources. Asafetida plant extract was prepared and studied their phytochemical characteristics to be used as insecticidal agent against c. pipiens. The total carbohydrate contents, polyphenolic contents, flavonoid contents and protein contents were found 51.90, 129.0, 10.27, and 366.67 mg/g, respectively. The greatest mortality percentage was observed at the concentration 1000 ppm (86.7%) and (80%) after 12 h and 24 h post treatment. In respect to the mortality rate the LC 50, LC 90 and LC 95 were found to be 352.1, 3154.8 and 4028.8 ppm. The total antioxidant values were significantly higher at the concentrations of 125 ppm and 1000 ppm (1.52, 1.49) through the first 12 h of the treatment as well as lipid per oxidation levels showed higher enzymatic levels of 3.6, 3.7 at 125, 250 ppm than those of the control group (0.11).The phenolic concentration increased gradually from 0 to 250 ppm ( 0.32, 1.32) then suppressed to (0.58) at 500 ppm. DPPH levels showed noticeable elevation through 12 h were (97.0) at 125 ppm while declined at 250 ppm till (95.6) to rise again at 500 ppm (97.3). SOD gradually increase at 500 ppm at 12 and 24 h (0.37, 0.36) than control while superoxide anion radical concentration levels presented as fluctuated from 0 to 1000 ppm.
据报道，数百种蚊子能够将疾病传播给人类。因此，全球范围内控制蚊子至关重要，尤其是在淡水源集中的地区。制备了阿魏植物提取物并研究了其植物化学特性，以用作针对尖音库蚊的杀虫剂。发现总碳水化合物含量、多酚含量、黄酮类含量和蛋白质含量分别为51.90、129.0、10.27和366.67毫克/克。在处理后12小时和24小时，在1000 ppm浓度下观察到最高死亡率（分别为86.7%和80%）。就死亡率而言，发现LC50、LC90和LC95分别为352.1、3154.8和4028.8 ppm。在处理的前12小时，125 ppm和1000 ppm浓度下的总抗氧化值显著更高（分别为1.52、1.49），并且脂质过氧化水平在125 ppm和250 ppm时显示出比对照组（0.11）更高的酶水平（分别为3.6、3.7）。酚类浓度从0到250 ppm逐渐增加（分别为0.32、1.32），然后在500 ppm时降至（0.58）。DPPH水平在12小时内显示出明显升高，在125 ppm时为（97.0），在250 ppm时下降至（95.6），在500 ppm时再次上升至（97.3）。超氧化物歧化酶在500 ppm、12小时和24小时时逐渐增加（分别为0.37、0.36），高于对照组，而超氧阴离子自由基浓度水平在0到1000 ppm之间波动。
