Department of Disease Control, London School of Hygiene & Tropical Medicine, Keppel Street, Bloomsbury, London WC1E 7HT, UK.
Centre for Virus Research, Bearsden Road, Bearsden, Glasgow G61 1QH, UK.
Philos Trans R Soc Lond B Biol Sci. 2021 Feb 15;376(1818):20190802. doi: 10.1098/rstb.2019.0802. Epub 2020 Dec 28.
Mosquito-borne diseases are an increasing global health challenge, threatening over 40% of the world's population. Despite major advances in malaria control since 2000, recent progress has stalled. Additionally, the risk of -borne arboviruses is rapidly growing, with the unprecedented spread of dengue and chikungunya viruses, outbreaks of yellow fever and the 2015 epidemic of Zika virus in Latin America. To counteract this growing problem, diverse and innovative mosquito control technologies are currently under development. Conceptually, these span an impressive spectrum of approaches, from invasive transgene cassettes with the potential to crash mosquito populations or reduce the vectorial capacity of a population, to low-cost alterations in housing design that restrict mosquito entry. This themed issue will present articles providing insight into the breadth of mosquito control research, while demonstrating the requirement for an interdisciplinary approach. The issue will highlight mosquito control technologies at varying stages of development and includes both opinion pieces and research articles with laboratory and field-based data on control strategy development. This article is part of the theme issue 'Novel control strategies for mosquito-borne diseases'.
蚊媒传染病是一个日益严重的全球健康挑战，威胁着全球超过 40%的人口。尽管自 2000 年以来疟疾控制取得了重大进展，但最近的进展已经停滞不前。此外，虫媒病毒的风险正在迅速增加，登革热和基孔肯雅热病毒的空前传播，黄热病的爆发以及 2015 年拉丁美洲的寨卡病毒流行。为了应对这一日益严重的问题，目前正在开发各种创新的蚊虫控制技术。从理论上讲，这些方法涵盖了广泛的范围，从具有潜在能力破坏蚊群或降低种群传播能力的侵入性转基因盒，到限制蚊虫进入的低成本住房设计改变。本期特刊将发表一些文章，深入了解蚊虫控制研究的广度，同时展示跨学科方法的必要性。该特刊将重点介绍处于不同开发阶段的蚊虫控制技术，包括观点文章和研究文章，其中包括关于控制策略开发的实验室和实地数据。本文是“蚊媒疾病的新型控制策略”主题特刊的一部分。
