Lee Sujung, Son Dae-Soon, Kim Jae-In, Lee Jungmin
School of Nursing, Hallym University, Chuncheon, 24252, Gangwon-Do, South Korea.
Department of Data Science and Data Science Convergence Research Center, Hallym University, Chuncheon, Gangwon-Do, 24252, Republic of Korea.
Sci Rep. 2025 Jul 25;15(1):27119. doi: 10.1038/s41598-025-13378-5.
Diabetes is a growing health concern among young adults; yet, most studies focus on older populations. This study aimed to examine the factors associated with prediabetes development in young adults. We carried out a cross-sectional study using data from the Korean National Health and Nutrition Examination Survey (KNHANES) for the period 2013-2021. Young adults were categorized into prediabetes (n = 2306) and normal glucose (n = 2306) groups. Propensity score matching was applied to control for age and sex, and multiple logistic regression was performed to identify significant predictors for prediabetes. The results showed that glycated hemoglobin had the highest adjusted Odds Ratio (OR = 2.27, p < 0.001), confirming its strong association with pre diabetes. Age group (OR = 2.27, p < 0.001), also showed a substantial effect, Sex (OR = 1.95, p < 0.001), physical activity (OR = 1.69, p < 0.001), Overweight (OR = 1.39, p < 0.0034) and Fasting blood sugar (OR = 1.33, p < 0.0034) were also significant predictors. However, alcohol consumption and underweight were not statistically significant. Metabolic indicators along with physical inactivity are critical factors influencing prediabetes in young adults. Early screening and targeted lifestyle interventions are essential in preventing diabetes progression, and reducing the risk of future health burdens.
糖尿病在年轻成年人中已成为一个日益严重的健康问题;然而,大多数研究聚焦于老年人群体。本研究旨在探讨与年轻成年人糖尿病前期发展相关的因素。我们利用2013 - 2021年韩国国家健康与营养检查调查(KNHANES)的数据开展了一项横断面研究。年轻成年人被分为糖尿病前期组(n = 2306)和正常血糖组(n = 2306)。应用倾向得分匹配法来控制年龄和性别,并进行多因素逻辑回归以确定糖尿病前期的显著预测因素。结果显示,糖化血红蛋白的调整优势比最高(OR = 2.27,p < 0.001),证实其与糖尿病前期有很强的关联。年龄组(OR = 2.27,p < 0.001)也显示出显著影响,性别(OR = 1.95,p < 0.001)、身体活动(OR = 1.69,p < 0.001)、超重(OR = 1.39,p < 0.0034)和空腹血糖(OR = 1.33,p < 0.0034)也是显著的预测因素。然而,饮酒和体重过轻在统计学上并不显著。代谢指标以及缺乏身体活动是影响年轻成年人糖尿病前期的关键因素。早期筛查和有针对性的生活方式干预对于预防糖尿病进展以及降低未来健康负担风险至关重要。