肽合成中存在争议的命名法：呼吁明确化。
Controversial Nomenclature in Peptide Synthesis: A Call for Clarity.
作者信息
Sharma Anamika, Kumar Ashish, de la Torre Beatriz G, Albericio Fernando
机构信息
Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa.
KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
出版信息
J Pept Sci. 2025 Sep;31(9):e70044. doi: 10.1002/psc.70044.
Various approaches to make peptides have been adopted globally owing to their high demand. The three main approaches commonly used for this purpose are solution synthesis, also called classical solution-phase peptide synthesis (CSPS), solid-phase peptide synthesis (SPPS), and liquid-phase peptide synthesis (LPPS). Each method offers unique advantages: CSPS for scalability, SPPS for automation and efficiency, and LPPS for combining solution-phase simplicity with iterative synthesis using soluble tags.
由于对肽的需求量很大，全球已采用了各种制备肽的方法。为此目的通常使用的三种主要方法是溶液合成，也称为经典溶液相肽合成（CSPS）、固相肽合成（SPPS）和液相肽合成（LPPS）。每种方法都有其独特的优势：CSPS具有可扩展性，SPPS具有自动化和高效性，LPPS则将溶液相的简单性与使用可溶性标签的迭代合成相结合。
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