Xu Piao, Jiang Han, Zheng Fei, Song Qian
Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Donghu District, 461 Bayi Avenue, Nanchang City, Jiangxi Province, 330006, China.
Department of Pathology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Donghu District, 461 Bayi Avenue, Nanchang City, Jiangxi Province, 330006, China.
J Surg Case Rep. 2025 Jul 26;2025(7):rjaf435. doi: 10.1093/jscr/rjaf435. eCollection 2025 Jul.
Thymic mucinous adenocarcinoma is an extremely rare and aggressive malignant tumor of the thymus with a very low 5-year survival rate. Here, we report a case of surgically resected primary mucinous adenocarcinoma of the thymus in a patient in his 60s who was admitted to the hospital with chest tightness for 2 weeks. The patient underwent median sternotomy and thymectomy, including resection of the brachiocephalic vein and partial resection of the superior vena cava wall. Histopathologic examination confirmed the diagnosis of mucinous adenocarcinoma, staged as pT2aN2M0 (IVB). Immunohistochemical analysis showed negative expression of CK20 and CK7, and preoperative carcinoembryonic antigen levels were within the normal range.
胸腺黏液腺癌是一种极其罕见且侵袭性强的胸腺恶性肿瘤，5年生存率极低。在此，我们报告一例60多岁因胸闷2周入院的患者，其原发性胸腺黏液腺癌经手术切除。患者接受了正中胸骨切开术和胸腺切除术，包括切除头臂静脉和部分上腔静脉壁。组织病理学检查确诊为黏液腺癌，分期为pT2aN2M0（IVB期）。免疫组化分析显示CK20和CK7呈阴性表达，术前癌胚抗原水平在正常范围内。
