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中国胸腺瘤专家共识(2023 版)

Chinese expert consensus on the diagnosis and treatment of thymic epithelial tumors.

机构信息

Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Hangzhou, People's Republic of China.

Department of Chemotherapy, Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital), Zhejiang, People's Republic of China.

出版信息

Thorac Cancer. 2023 Apr;14(12):1102-1117. doi: 10.1111/1759-7714.14847. Epub 2023 Mar 16.

Abstract

Thymic epithelial tumors (TETs) are a relatively rare type of thoracic tumor, accounting for less than 1% of all tumors. The incidence of TETs is about 3.93/10000 in China, slightly higher than that of European and American countries. For resectable TETs, complete surgical resection is recommended. Radiotherapy or chemotherapy may be used as postoperative adjuvant treatment. Treatment for advanced, unresectable TETs consist mainly of radiotherapy and chemotherapy, but there is a lack of standard first- and second-line treatment regimens. Recently, targeted therapies and immune checkpoint inhibitors have shown promising outcomes in TETs. Based on the currently available clinical evidences and the opinions of the national experts, the Thymic Oncology Group of Yangtze River Delta Lung Cancer Cooperation Group (East China LUng caNcer Group, ECLUNG; Youth Committee) established this Chinese expert consensus on the clinical diagnosis and treatment of TETs, covering the epidemiology, diagnosis, treatment, prognosis and follow-up of TETs.

摘要

胸腺上皮肿瘤(TETs)是一种相对罕见的胸部肿瘤,占所有肿瘤的比例不到 1%。在中国,TETs 的发病率约为 3.93/10000,略高于欧美国家。对于可切除的 TETs,建议行完全手术切除。术后可采用放疗或化疗作为辅助治疗。对于晚期、不可切除的 TETs,主要治疗方法为放疗和化疗,但缺乏标准的一线和二线治疗方案。最近,靶向治疗和免疫检查点抑制剂在 TETs 中显示出良好的疗效。基于目前的临床证据和全国专家的意见,长三角肺癌合作组(华东肺癌协作组,ECLUNG;青年委员会)胸腺肿瘤专家组制定了本中国 TETs 临床诊疗专家共识,涵盖了 TETs 的流行病学、诊断、治疗、预后和随访。

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