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本文引用的文献

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Pediatr Nephrol. 2024 Jan;39(1):125-129. doi: 10.1007/s00467-023-06079-6. Epub 2023 Jul 14.
2
Hyperkalemia in Diabetes Mellitus Setting.糖尿病环境下的高钾血症
Diseases. 2022 Mar 28;10(2):20. doi: 10.3390/diseases10020020.
3
Clinical features, genetic background, and outcome in infants with urinary tract infection and type IV renal tubular acidosis.尿路感染合并 IV 型肾小管性酸中毒婴儿的临床特征、遗传背景和结局。
Pediatr Res. 2020 Jun;87(7):1251-1255. doi: 10.1038/s41390-019-0727-7. Epub 2019 Dec 18.
4
Hyperkalemic Forms of Renal Tubular Acidosis: Clinical and Pathophysiological Aspects.高钾血症型肾小管酸中毒:临床与病理生理学方面。
Adv Chronic Kidney Dis. 2018 Jul;25(4):321-333. doi: 10.1053/j.ackd.2018.05.004.
5
Pharmacology behind Common Drug Nephrotoxicities.常见药物肾毒性的药理学基础。
Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1897-1908. doi: 10.2215/CJN.00150118. Epub 2018 Apr 5.
6
Diabetes mellitus and hyperkalemic renal tubular acidosis: case reports and literature review.糖尿病与高钾性肾小管酸中毒:病例报告及文献综述
J Bras Nefrol. 2017 Oct-Dec;39(4):481-485. doi: 10.5935/0101-2800.20170086.
7
Tacrolimus-Induced Type IV Renal Tubular Acidosis following Liver Transplantation.肝移植后他克莫司诱导的IV型肾小管酸中毒
Case Reports Hepatol. 2017;2017:9312481. doi: 10.1155/2017/9312481. Epub 2017 Jul 6.
8
Review of the Diagnostic Evaluation of Renal Tubular Acidosis.肾小管酸中毒的诊断评估综述。
Ochsner J. 2016 Winter;16(4):525-530.
9
Clinical analysis of hyperkalemic renal tubular acidosis caused by calcineurin inhibitors in solid organ transplant recipients.实体器官移植受者中钙调神经磷酸酶抑制剂所致高钾性肾小管酸中毒的临床分析
J Clin Pharm Ther. 2017 Feb;42(1):122-124. doi: 10.1111/jcpt.12485. Epub 2016 Dec 14.
10
Type 4 renal tubular acidosis in a kidney transplant recipient.肾移植受者的4型肾小管酸中毒
Biomed J. 2016 Feb;39(1):85-6. doi: 10.1016/j.bj.2015.08.008. Epub 2016 Mar 29.

糖尿病患者高钾血症被低估的原因:IV型肾小管酸中毒——综述

Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review.

作者信息

Ertek Sibel, Caglar Kayser

机构信息

Endocrinology and Metabolic Diseases Department, Losante Hospital, Ankara, Türkiye.

Nephrology Department, Losante Hospital, Ankara, Türkiye.

出版信息

Front Clin Diabetes Healthc. 2025 Jul 11;6:1570868. doi: 10.3389/fcdhc.2025.1570868. eCollection 2025.

DOI:10.3389/fcdhc.2025.1570868
PMID:40717832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12289468/
Abstract

Diabetes mellitus is chronic disease with increasing prevalence, and may cause many organ complications, including kidneys. Reduced creatinine clearance and kidney failure are important, but hyperkalemia may be present in diabetic patients even before these problems. There may be many reasons of hyperkalemia in this group of patients. Type IV renal tubular acidosis is important cause of generally mild hyperkalemia, and it is a treatable condition. ''Polypharmacy'' -which is very common in diabetic patients due to accompanying other diseases- may trigger electrolyte imbalance. Underlying causes should be investigated and treatment should be done before it worsens.

摘要

糖尿病是一种患病率不断上升的慢性疾病,可能会引发包括肾脏在内的许多器官并发症。肌酐清除率降低和肾衰竭很重要,但糖尿病患者甚至在出现这些问题之前就可能存在高钾血症。这组患者出现高钾血症的原因可能有很多。IV型肾小管酸中毒是导致一般轻度高钾血症的重要原因,且是一种可治疗的病症。“多重用药”——由于合并其他疾病,在糖尿病患者中非常常见——可能引发电解质失衡。应调查潜在病因并在病情恶化前进行治疗。