Jha Adarsh, Jha Divij K, Joshi Amey U, Pandey Samiksha, Ahmad Fariah K
Internal Medicine, Michigan State University, Lansing, USA.
Gastroenterology and Hepatology, Oakland University William Beaumont Hospital, Royal Oak, USA.
Cureus. 2025 Jun 27;17(6):e86876. doi: 10.7759/cureus.86876. eCollection 2025 Jun.
() is an uncommon gastric pathogen increasingly recognized for its role in gastrointestinal diseases. Unlike (), is rarely detected and often overlooked. It is typically associated with milder pathological features, including less neutrophilic activity, reduced mononuclear infiltration, and endoscopic signs of chronic gastritis without erosions or ulcers. We report a case of a 71-year-old female patient with a history of invasive breast carcinoma who presented with dysphagia, nausea, and dyspepsia following chemoradiotherapy. Initial endoscopy revealed esophageal strictures and erosive gastritis, with biopsies negative for . Persistent symptoms prompted repeat endoscopic evaluation, which demonstrated on histology. The patient responded well to bismuth quadruple therapy, with complete symptom resolution and eradication of the infection. This case underscores the need to consider as an uncommon but potential cause of unexplained erosive gastritis or peptic ulcer disease, given its typically milder histopathologic features, such as reduced neutrophilic and mononuclear infiltration and subtle endoscopic findings, which may contribute to underdiagnosis. Prompt recognition and treatment can lead to excellent clinical outcomes and may reduce the risk of long-term complications such as mucosa-associated lymphoid tissue (MALT) lymphoma.
（）是一种不常见的胃部病原体，其在胃肠道疾病中的作用日益受到认可。与（）不同，（）很少被检测到且常常被忽视。它通常与较轻的病理特征相关，包括中性粒细胞活性较低、单核细胞浸润减少以及无糜烂或溃疡的慢性胃炎的内镜表现。我们报告一例71岁女性患者，有浸润性乳腺癌病史，在放化疗后出现吞咽困难、恶心和消化不良。初次内镜检查显示食管狭窄和糜烂性胃炎，活检未发现（）。持续的症状促使再次进行内镜评估，组织学检查显示存在（）。该患者对铋剂四联疗法反应良好，症状完全缓解且感染得以根除。鉴于其通常较轻的组织病理学特征，如中性粒细胞和单核细胞浸润减少以及细微的内镜检查结果，这可能导致诊断不足，该病例强调需要将（）视为不明原因糜烂性胃炎或消化性溃疡疾病的一种不常见但潜在的病因。及时识别和治疗可带来良好的临床结果，并可能降低诸如黏膜相关淋巴组织（MALT）淋巴瘤等长期并发症的风险。
