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在编码时恢复记忆的时间背景会导致类似西西弗斯式的记忆恢复活力。

Reinstating memories' temporal context at encoding causes Sisyphus-like memory rejuvenation.

作者信息

Bäuml Karl-Heinz T, Meixensperger Sarah R, Hirsch Marilena L

机构信息

Department of Experimental Psychology, Regensburg University, Regensburg 93053, Germany.

出版信息

Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e2505120122. doi: 10.1073/pnas.2505120122. Epub 2025 Jul 28.

Abstract

As memories age, their immediate retrievability decreases albeit, due to ongoing memory consolidation, their future rate of forgetting weakens. Here, we show in two experiments ( = 1.216 participants) that mentally traveling back in time to older memories' temporal context at encoding reverses the two effects and makes the memories similar again to how they were at an earlier point in time. Mental time travel increased both the memories' immediate retrievability and their future rate of forgetting when individuals attempted to reinstate context deliberately and actively and when they retrieved other memories sharing a similar temporal context. Intriguingly, the forgetting after mental time travel even followed the same trajectory as the forgetting after encoding. Attempts to reinstate memories' encoding context thus rejuvenated memories, although the degree of rejuvenation decreased as temporal lag between encoding and the reinstatement attempts increased, which was mediated by the fact that, with increasing lag, decreasing proportions of the encoded memories were reactivated and reconsolidated in response to participants' reinstatement attempts. Mentally traveling back in time creates rejuvenation cycles with enhanced retrievability followed by a restart of forgetting and consolidation processes. Recurring rejuvenation cycles may thus be key to maintain memories' retrievability over longer periods of time, painting the picture of Sisyphus-like memory resurrection.

摘要

随着记忆的老化,其即时可提取性会下降,尽管由于记忆巩固过程的持续进行,其未来的遗忘速度会减缓。在此,我们在两项实验(共1216名参与者)中表明,在编码时通过心理时光旅行回到旧记忆的时间背景,可以逆转这两种效应,使记忆再次变得与它们在更早时间点时相似。当个体有意且积极地试图恢复情境时,以及当他们提取共享相似时间背景的其他记忆时,心理时光旅行会同时提高记忆的即时可提取性及其未来的遗忘速度。有趣的是,心理时光旅行后的遗忘甚至遵循与编码后遗忘相同的轨迹。因此,试图恢复记忆的编码情境能使记忆恢复活力,尽管随着编码与恢复尝试之间的时间间隔增加,恢复活力的程度会降低,这是由以下事实介导的:随着时间间隔的增加,响应参与者的恢复尝试而被重新激活和重新巩固的编码记忆比例不断下降。心理时光旅行会创造出具有增强可提取性的恢复活力周期,随后遗忘和巩固过程重新开始。因此,反复出现的恢复活力周期可能是在更长时间段内维持记忆可提取性的关键,描绘出一幅类似西西弗斯式的记忆复苏图景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5102/12358906/e8003cc2938d/pnas.2505120122fig01.jpg

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