Zhang Jiali, Zhong Muhan, Fan Shuqi, Chang Xindan, Li Xue, Chen Hao, Bao Jinhua, Huang Yingying
National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
BMC Ophthalmol. 2025 Jul 28;25(1):427. doi: 10.1186/s12886-025-04257-8.
To explore the repeatability, reproducibility and agreement for three optical coherence tomography (OCT) in measuring retinal (RT) and choroidal thickness (ChT).
Sixty-eight eyes were included. The average RT and ChT were obtained with VG200I and Triton, while only the subfoveal RT (SFRT) and ChT (SFChT) were measured with RTVue. Operator 1 conducted two examinations to assess repeatability, and operator 2 conducted one for reproducibility. Built-in software was used to calculate RT-auto and ChT-auto, and custom-designed algorithms were used to calculate ChT-custom to assess interanalysis and intermachine agreements.
The intraclass correlation coefficients for the repeatability and reproducibility were larger than 0.760 and 0.940 with VG200I, 0.890 and 0.910 with Triton, and 0.960 and 0.975 with RTVue, respectively. The intermachine differences for SFRT and SFChT were - 8.82 ± 3.15 μm and - 41.89 ± 8.21 μm (VG200I vs. RTVue), -26.86 ± 3.15 μm and - 56.60 ± 7.81 μm (Triton vs. RTVue), and 18.04 ± 2.01 μm and 14.71 ± 3.02 μm (VG200I vs. Triton), respectively. The mean differences between VG200I and Triton in RT, ChT-auto and ChT-custom across the different regions ranged between 16.34 and 27.80 μm, 66.53 and 96.93 μm, and 4.48 and 18.32 μm, respectively. The mean differences between ChT-auto and ChT-custom across the different regions ranged between 29.06 and 43.71 μm for VG200I and - 48.73 and - 27.98 μm for Triton. The intermachine correlations were high, with ρ > 0.655 for all parameters.
The three OCT devices all showed great repeatability and reproducibility, while the agreements between them were poor.
探讨三种光学相干断层扫描（OCT）测量视网膜（RT）和脉络膜厚度（ChT）的可重复性、再现性及一致性。
纳入68只眼。使用VG200I和Triton获取平均RT和ChT，而仅用RTVue测量黄斑中心凹下RT（SFRT）和ChT（SFChT）。操作人员1进行两次检查以评估可重复性，操作人员2进行一次检查以评估再现性。使用内置软件计算RT自动测量值和ChT自动测量值，使用定制算法计算ChT定制测量值以评估分析间和仪器间的一致性。
VG200I测量的可重复性和再现性的组内相关系数分别大于0.760和0.940，Triton测量的分别为0.890和0.910，RTVue测量的分别为0.960和0.975。SFRT和SFChT的仪器间差异分别为-8.82±3.15μm和-41.89±8.21μm（VG200I与RTVue）、-26.86±3.15μm和-56.60±7.81μm（Triton与RTVue）、18.04±2.01μm和14.71±3.02μm（VG200I与Triton）。不同区域中VG200I和Triton在RT、ChT自动测量值和ChT定制测量值方面的平均差异分别在16.34至27.80μm、66.53至96.93μm和4.48至18.32μm之间。不同区域中ChT自动测量值和ChT定制测量值之间的平均差异，VG200I在29.06至43.71μm之间，Triton在-48.73至-27.98μm之间。仪器间相关性较高，所有参数的ρ>0.655。
三种OCT设备均显示出良好的可重复性和再现性，但它们之间的一致性较差。
