• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用可穿戴传感器融合与深度学习的自动统一帕金森病评定量表步态评分

Automated UPDRS Gait Scoring Using Wearable Sensor Fusion and Deep Learning.

作者信息

Liu Xiangzhi, Zhang Xiangliang, Li Juan, Pan Wenhao, Sun Yiping, Lin Shuanggen, Liu Tao

机构信息

The State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China.

Beijing Research Institute of Mechanical and Electrical Engineering, Beijing 102202, China.

出版信息

Bioengineering (Basel). 2025 Jun 24;12(7):686. doi: 10.3390/bioengineering12070686.

DOI:10.3390/bioengineering12070686
PMID:40722378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12292898/
Abstract

The quantitative assessment of Parkinson's disease (PD) is critical for guiding diagnosis, treatment, and rehabilitation. Conventional clinical evaluations-heavily dependent on manual rating scales such as the Unified Parkinson's Disease Rating Scale (UPDRS)-are time-consuming and prone to inter-rater variability. In this study, we propose a fully automated UPDRS gait-scoring framework. Our method combines (a) surface electromyography (EMG) signals and (b) inertial measurement unit (IMU) data into a single deep learning model. Our end-to-end network comprises three specialized branches-a diagnosis head, an evaluation head, and a balance head-whose outputs are integrated via a customized fusion-detection module to emulate the multidimensional assessments performed by clinicians. We validated our system on 21 PD patients and healthy controls performing a simple walking task while wearing a four-channel EMG array on the lower limbs and 2 shank-mounted IMUs. It achieved a mean classification accuracy of 92.8% across UPDRS levels 0-2. This approach requires minimal subject effort and sensor setup, significantly cutting clinician workload associated with traditional UPDRS evaluations while improving objectivity. The results demonstrate the potential of wearable sensor-driven deep learning methods to deliver rapid, reliable PD gait assessment in both clinical and home settings.

摘要

帕金森病(PD)的定量评估对于指导诊断、治疗和康复至关重要。传统的临床评估严重依赖于诸如统一帕金森病评定量表(UPDRS)等手动评分量表,既耗时又容易出现评分者间的差异。在本研究中,我们提出了一个全自动的UPDRS步态评分框架。我们的方法将(a)表面肌电图(EMG)信号和(b)惯性测量单元(IMU)数据结合到一个单一的深度学习模型中。我们的端到端网络包括三个专门的分支——一个诊断头、一个评估头和一个平衡头,其输出通过一个定制的融合检测模块进行整合,以模拟临床医生进行的多维评估。我们在21名PD患者和健康对照者身上验证了我们的系统,他们在执行简单步行任务时,下肢佩戴四通道EMG阵列,小腿安装2个IMU。在UPDRS 0 - 2级中,其平均分类准确率达到了92.8%。这种方法所需的受试者努力和传感器设置最少,显著减少了与传统UPDRS评估相关的临床医生工作量,同时提高了客观性。结果表明,可穿戴传感器驱动的深度学习方法在临床和家庭环境中都有提供快速、可靠的PD步态评估的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/62287dc81d37/bioengineering-12-00686-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/016b377548f8/bioengineering-12-00686-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/84aaa4ecb3b9/bioengineering-12-00686-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/d453d2679772/bioengineering-12-00686-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/578578f686d7/bioengineering-12-00686-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/9b271eefc03d/bioengineering-12-00686-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/4bf034fd2fa2/bioengineering-12-00686-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/43dcda960e86/bioengineering-12-00686-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/83a3e01626f2/bioengineering-12-00686-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/85af4ac6f8f1/bioengineering-12-00686-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/ac0c06fed32e/bioengineering-12-00686-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/62287dc81d37/bioengineering-12-00686-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/016b377548f8/bioengineering-12-00686-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/84aaa4ecb3b9/bioengineering-12-00686-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/d453d2679772/bioengineering-12-00686-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/578578f686d7/bioengineering-12-00686-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/9b271eefc03d/bioengineering-12-00686-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/4bf034fd2fa2/bioengineering-12-00686-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/43dcda960e86/bioengineering-12-00686-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/83a3e01626f2/bioengineering-12-00686-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/85af4ac6f8f1/bioengineering-12-00686-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/ac0c06fed32e/bioengineering-12-00686-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10d/12292898/62287dc81d37/bioengineering-12-00686-g011.jpg

相似文献

1
Automated UPDRS Gait Scoring Using Wearable Sensor Fusion and Deep Learning.使用可穿戴传感器融合与深度学习的自动统一帕金森病评定量表步态评分
Bioengineering (Basel). 2025 Jun 24;12(7):686. doi: 10.3390/bioengineering12070686.
2
Improving reliability of movement assessment in Parkinson's disease using computer vision-based automated severity estimation.利用基于计算机视觉的自动严重程度估计提高帕金森病运动评估的可靠性。
J Parkinsons Dis. 2025 Mar;15(2):349-360. doi: 10.1177/1877718X241312605. Epub 2025 Feb 13.
3
Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.帕金森病患者的身体锻炼:系统评价和网络荟萃分析。
Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.
4
Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.帕金森病患者的体育锻炼:系统评价与网状Meta分析
Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.
5
Gait parameters and daily physical activity for distinguishing pre-frail, frail, and non-frail older adults: A scoping review.用于区分衰弱前期、衰弱和非衰弱老年人的步态参数及日常身体活动:一项范围综述
J Nutr Health Aging. 2025 May 14;29(7):100580. doi: 10.1016/j.jnha.2025.100580.
6
Physiotherapy versus placebo or no intervention in Parkinson's disease.帕金森病中物理治疗与安慰剂或无干预的对比
Cochrane Database Syst Rev. 2013 Sep 10;2013(9):CD002817. doi: 10.1002/14651858.CD002817.pub4.
7
Depressive symptoms can negatively influence patient reported disease severity after subthalamic nucleus stimulation for Parkinson's disease.对于帕金森病患者,在接受丘脑底核刺激后,抑郁症状会对患者报告的疾病严重程度产生负面影响。
J Parkinsons Dis. 2025 Jun 26:1877718X251354933. doi: 10.1177/1877718X251354933.
8
Your turn: At home turning angle estimation for Parkinson's disease severity assessment.轮到你了:用于帕金森病严重程度评估的居家转身角度估计。
Artif Intell Med. 2025 Sep;167:103194. doi: 10.1016/j.artmed.2025.103194. Epub 2025 Jun 18.
9
Detecting Freezing of Gait in Parkinson Disease Using Multiple Wearable Sensors Sets During Various Walking Tasks Relative to Medication Conditions (DetectFoG): Protocol for a Prospective Cohort Study.在帕金森病中使用多个可穿戴传感器集在与药物治疗情况相关的各种步行任务期间检测步态冻结(DetectFoG):一项前瞻性队列研究的方案
JMIR Res Protoc. 2025 Feb 6;14:e58612. doi: 10.2196/58612.
10
Motor outcomes in unilateral, bilateral rapid, and bilateral delayed staging deep brain stimulation for Parkinson's disease.帕金森病单侧、双侧快速和双侧延迟分期脑深部电刺激的运动结果
J Parkinsons Dis. 2024 Nov;14(8):1614-1622. doi: 10.1177/1877718X241296014. Epub 2024 Dec 8.

本文引用的文献

1
A Novel Approach for Visual Speech Recognition Using the Partition-Time Masking and Swin Transformer 3D Convolutional Model.一种使用分区时间掩码和Swin Transformer 3D卷积模型的视觉语音识别新方法。
Sensors (Basel). 2025 Apr 8;25(8):2366. doi: 10.3390/s25082366.
2
EEG-based emotion recognition with autoencoder feature fusion and MSC-TimesNet model.基于脑电图的情感识别与自动编码器特征融合及MSC-TimesNet模型
Comput Methods Biomech Biomed Engin. 2025 Mar 17:1-18. doi: 10.1080/10255842.2025.2477801.
3
Development of a Wearable Electromyographic Sensor with Aerosol Jet Printing Technology.
采用气溶胶喷射印刷技术开发可穿戴肌电图传感器。
Bioengineering (Basel). 2024 Dec 17;11(12):1283. doi: 10.3390/bioengineering11121283.
4
Gait analysis in the early stage of Parkinson's disease with a machine learning approach.基于机器学习方法的帕金森病早期步态分析。
Front Neurol. 2024 Oct 8;15:1472956. doi: 10.3389/fneur.2024.1472956. eCollection 2024.
5
Unveiling the Unpredictable in Parkinson's Disease: Sensor-Based Monitoring of Dyskinesias and Freezing of Gait in Daily Life.揭示帕金森病中的不可预测因素:基于传感器的日常生活中异动症和步态冻结监测
Bioengineering (Basel). 2024 Apr 29;11(5):440. doi: 10.3390/bioengineering11050440.
6
Sensor-Based Quantification of MDS-UPDRS III Subitems in Parkinson's Disease Using Machine Learning.基于传感器的帕金森病 MDS-UPDRS III 亚项的机器学习量化。
Sensors (Basel). 2024 Mar 29;24(7):2195. doi: 10.3390/s24072195.
7
5G NB-IoT System Integrated with High-Performance Fiber Sensor Inspired by Cirrus and Spider Structures.受卷云和蜘蛛结构启发的集成高性能光纤传感器的5G窄带物联网系统
Adv Sci (Weinh). 2024 May;11(18):e2309894. doi: 10.1002/advs.202309894. Epub 2024 Mar 9.
8
An IMU-Based Ground Reaction Force Estimation Method and Its Application in Walking Balance Assessment.基于惯性测量单元的地面反力估计方法及其在行走平衡评估中的应用。
IEEE Trans Neural Syst Rehabil Eng. 2024;32:223-232. doi: 10.1109/TNSRE.2023.3347729. Epub 2024 Jan 15.
9
Validity of artificial intelligence-based markerless motion capture system for clinical gait analysis: Spatiotemporal results in healthy adults and adults with Parkinson's disease.基于人工智能的无标记运动捕捉系统用于临床步态分析的有效性:健康成年人和帕金森病成年人的时空结果。
J Biomech. 2023 Jun;155:111645. doi: 10.1016/j.jbiomech.2023.111645. Epub 2023 May 19.
10
Automatic Assessments of Parkinsonian Gait with Wearable Sensors for Human Assistive Systems.基于可穿戴传感器的帕金森步态自动评估及其在人体辅助系统中的应用。
Sensors (Basel). 2023 Feb 13;23(4):2104. doi: 10.3390/s23042104.