Jin Eric, Wong Natalie Shi Qi, Goh Claire Xin Yi, Stewart Michael W, Dorairaj Syril, Ang Bryan Chin Hou
Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Department of Ophthalmology, Tan Tock Seng Hospital, National Healthcare Group Eye Institute, Singapore 308433, Singapore.
Bioengineering (Basel). 2025 Jun 29;12(7):711. doi: 10.3390/bioengineering12070711.
A systematic review was conducted of studies published up to 30 August 2024. Studies comparing conventional visual field (VF) indices, ability to detect central visual field defects (CVFDs), structure-function (S-F) concordance, and test characteristics across the HVF 24-2C SITA-Faster, 24-2 SITA-Standard/Faster, and 10-2 SITA-Standard/Fast tests were included. Eight studies with 1239 subjects (49.1% male; mean age, 54.8-66.9 years) were analyzed. The 24-2C produced similar global VF indices compared to the 10-2 and 24-2 (Standard/Faster) (ICC = 0.95 and 0.80, < 0.001), detected more VF defects and CVFD clusters, and demonstrated greater S-F concordance than the 24-2 (Standard/Faster). Although the 10-2 (Standard/Fast) detected significantly more CVFDs and had a greater S-F concordance, the agreement between the 24-2C and 10-2 grids was substantial (ĸ = 0.488 to 0.708). The 24-2C was also faster compared to the 24-2 Standard and 10-2 (Standard/Fast), with comparable false positives, higher false negatives, and fewer fixation losses than the 24-2 Standard. In conclusion, the HVF 24-2C is quicker and identifies more CVFDs than the 24-2 grid, demonstrates high agreement with the 10-2 grid, and aids in CVFD screening.
对截至2024年8月30日发表的研究进行了系统综述。纳入了比较传统视野（VF）指标、检测中心视野缺损（CVFD）的能力、结构-功能（S-F）一致性以及在HVF 24-2C SITA-Faster、24-2 SITA-Standard/Faster和10-2 SITA-Standard/Fast测试中的测试特征的研究。分析了八项研究，共1239名受试者（49.1%为男性；平均年龄54.8 - 66.9岁）。与10-2和24-2（Standard/Faster）相比，24-2C产生的整体VF指标相似（组内相关系数[ICC]=0.95和0.80，P<0.001），检测到更多的VF缺损和CVFD簇，并且与24-2（Standard/Faster）相比显示出更高的S-F一致性。虽然10-2（Standard/Fast）检测到的CVFD明显更多且具有更高的S-F一致性，但24-2C和10-2网格之间的一致性较高（ĸ=0.488至0.708）。与24-2 Standard和10-2（Standard/Fast）相比，24-2C也更快，假阳性相当，假阴性高于24-2 Standard，固视丢失少于24-2 Standard。总之，与24-2网格相比，HVF 24-2C更快且能识别更多的CVFD，与10-2网格高度一致，有助于CVFD筛查。
