Dugal Jasmine K, Malhi Arpinder S, Singh Yuvraj, Razmi Rooz, Vance Joshua, Sharma Divyansh
Department of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada Las Vegas, Las Vegas, NV 89102, USA.
Lake Erie College of Osteopathic Medicine (LECOM), Erie, PA 16509, USA.
Biomedicines. 2025 Jun 27;13(7):1580. doi: 10.3390/biomedicines13071580.
Heart failure is a heterogeneous disorder that can lead to cardiogenic shock. Mechanical circulatory support (MCS) devices can replace the cardiac function in an attempt to bridge patients to transplant or they can serve as destination therapy to improve overall patient functionality and in turn quality of life. Currently utilized MCS devices include devices such as Left Ventricular Assist Devices (LVADs), Biventricular Assist Devices (BiVADs), Impella, Total Artificial Hearts (TAHs), and extracorporeal membrane oxygenation (ECMO). This literature review examines a range of studies, case reports, and meta-analyses to present current approaches to mechanical circulatory support (MCS), along with the challenges and limitations of existing devices, common complications, and overall survival and long-term outcomes following MCS therapy.
心力衰竭是一种异质性疾病，可导致心源性休克。机械循环支持（MCS）设备可以替代心脏功能，试图使患者过渡到移植阶段，或者作为终末期治疗以改善患者的整体功能，进而提高生活质量。目前使用的MCS设备包括左心室辅助装置（LVAD）、双心室辅助装置（BiVAD）、Impella、全人工心脏（TAH）和体外膜肺氧合（ECMO）等。这篇文献综述研究了一系列研究、病例报告和荟萃分析，以介绍机械循环支持（MCS）的当前方法，以及现有设备的挑战和局限性、常见并发症，以及MCS治疗后的总体生存率和长期预后。
