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新生儿期急性肾损伤:回顾性数据及对临床实践的启示

Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice.

作者信息

Greenberg Meidad, Sity-Harel Saray, Benchetrit Sydney, Reisman Lewis, Zitman-Gal Tali, Erez Daniel, Shehab Maysam, Cohen-Hagai Keren

机构信息

Department of Pediatrics, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba 4428164, Israel.

Department of Nephrology and Hypertension, Meir Medical Center, Kfar Saba 4428164, Israel.

出版信息

Children (Basel). 2025 Jul 3;12(7):883. doi: 10.3390/children12070883.

Abstract

: Neonates, particularly those born prematurely or with low birth weight, face an elevated risk of developing Acute Kidney Injury (AKI) due to various factors. Perinatal and maternal considerations, often linked to preterm delivery, contribute to this heightened risk. : A retrospective study of neonates admitted to the intensive care unit at a single Israeli Hospital who were diagnosed as having AKI. The study includes follow-up data on these children. : During the study period, 971 neonates were admitted to the Pediatric Intensive Care Unit (PICU), and 47 cases had a documented diagnosis of AKI. Thirty-four of them had available long-term data and were included in this analysis. A total of 13 out of 26 subjects with available blood pressure measurements had high blood pressure for their age percentile compatible with the definition of hypertension, and 6 out of 34 (17.6%) had proteinuria. : These findings underscore the importance of increased clinical awareness and structured long-term follow-up for neonates who experience AKI.

摘要

新生儿,尤其是那些早产或低出生体重的新生儿,由于各种因素,发生急性肾损伤(AKI)的风险较高。围产期和母亲方面的因素,通常与早产有关,导致了这种风险的增加。:对一家以色列医院重症监护病房收治的被诊断为AKI的新生儿进行的回顾性研究。该研究包括这些儿童的随访数据。:在研究期间,971名新生儿被收治入儿科重症监护病房(PICU),其中47例有记录诊断为AKI。其中34例有可用的长期数据并纳入本分析。在26名有可用血压测量值的受试者中,共有13名按年龄百分位数计算血压高,符合高血压定义,34名中有6名(17.6%)有蛋白尿。:这些发现强调了提高对发生AKI的新生儿的临床认识以及进行结构化长期随访的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6a9/12293746/ef9d6422cf42/children-12-00883-g001.jpg

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