Schaedel H, Haenselt V, Kirsten D, Eger H
Z Gesamte Inn Med. 1985 Sep 15;40(18):555-6.
24 patients with pulmonary sarcoidosis stage I or II, who above all on account of changes of the ECG roused the suspicion of the presence of a sarcoidosis of the myocardium, finally underwent an invasive examination with laevocardiography, coronarography and biopsy of the endomyocardium. While the unaimed taking of tissue from the left ventricle did not result light-microscopically in a reference to granulomas or other inflammatory changes, the biopsy in a female patient, on purpose taken from a hypokinetic area of the left ventricle, showed epitheloid-cellular granulomas with giant-cells. Evaluating these results and reports in literatur, we came to the conclusion that findings typical for sarcoidosis are promising success only when taken from cardiographically suspicious areas of the myocardium.
24例I期或II期肺结节病患者,主要因心电图改变而怀疑存在心肌结节病,最终接受了左心导管检查、冠状动脉造影和心内膜活检等侵入性检查。虽然从左心室随机取材在光学显微镜下未发现肉芽肿或其他炎症改变,但在一名女性患者中,特意从左心室运动减弱区域取材的活检显示有上皮样细胞肉芽肿和巨细胞。综合这些结果以及文献报道,我们得出结论,只有从心肌心电图可疑区域取材,结节病的典型表现才有望获得成功诊断。