石榴酸：石榴籽油中的一种潜在营养化合物及其心血管益处。

Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits.

作者信息

Almoraie Manal, Spencer Jeremy, Wagstaff Carol

机构信息

Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading RG6 6DZ, UK.

Department of Food Science and Nutrition, Faculty of Human Sciences and Design, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

出版信息

Foods. 2025 Jul 8;14(14):2412. doi: 10.3390/foods14142412.

DOI:10.3390/foods14142412

PMID:40724233

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12294333/

Abstract

Pomegranate seed oil (PSO) is rich in punicic acid (PA), a conjugated isomer of α-linolenic acid, and exhibits a range of pharmacological properties. Given the significant role of nutraceuticals in the prevention of various diseases, PA stands out as an important phytoconstituent within this category. This review aimed to examine the composition of PSOs and their positive effects on cardiovascular risk factors. PA possesses potent antioxidant and anti-inflammatory effects, as well as aids in managing obesity and diabetes while improving lipid profiles. Additionally, the diverse cardiovascular health benefits associated with PSO consumption are detailed. There are various health benefits that are derived from PSO consumption; however, despite these promising findings, there remains a critical need for further clinical studies to validate these effects.

摘要

石榴籽油（PSO）富含石榴酸（PA），它是α-亚麻酸的共轭异构体，并具有一系列药理特性。鉴于营养保健品在预防各种疾病方面的重要作用，PA作为该类别中的一种重要植物成分脱颖而出。本综述旨在研究石榴籽油的成分及其对心血管危险因素的积极影响。PA具有强大的抗氧化和抗炎作用，有助于控制肥胖和糖尿病，同时改善血脂状况。此外，还详细阐述了食用石榴籽油对心血管健康的多种益处。食用石榴籽油有多种健康益处；然而，尽管有这些令人鼓舞的发现，但仍迫切需要进一步的临床研究来验证这些效果。