Perperidi Maria, Skeparnakou Eleni, Strongylou Dimitra, Leptopoulou Ariadni, Tsiampalis Thomas, Tsapakidis Konstantinos, Saloustros Emmanouil, Theodorakis Yannis, Androutsos Odysseas
Laboratory of Clinical Nutrition and Dietetics, Department of Nutrition and Dietetics, School of Physical Education, Sport Science and Dietetics, University of Thessaly, 42132 Trikala, Greece.
Oncology Unit, 3rd Department of Medicine, 'Sotiria' General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Healthcare (Basel). 2025 Jul 12;13(14):1683. doi: 10.3390/healthcare13141683.
Weight gain is frequently observed during and following breast cancer therapy. Women with overweight/obesity have poorer breast cancer prognoses and are more likely to develop comorbidities. The present study describes the development and qualitative assessment of the acceptability of the NutriLife study, a lifestyle weight management intervention with dietetic counseling and digital tools for breast cancer survivors (BCSs). The intervention was developed using the Medical Research Council (MRC) framework, informed by a systematic literature review and stakeholder input. Acceptability was assessed using the Theoretical Framework of Acceptability (TFA). A total of 22 BCSs with overweight/obesity participated in focus groups, and 5 dietitians/nutritionists specializing in breast cancer in Greece participated in semi-structured interviews. The data were further analyzed using thematic analysis. Stakeholders assessed the intervention as acceptable across all TFA constructs. The intervention was characterized as supportive, easily adaptable, time-efficient, well-organized, beneficial, and professionally driven, with potential barriers including limited personal time, inadequate digital literacy, insufficient self-care, and lack of commitment. Gradually increasing goals may be helpful and less stressful, while educational resources enhance focus on these objectives, thus encouraging intervention participation. Ensuring confidentiality was perceived as central to promoting health. The evidence-based, co-participatory design of the NutriLife intervention was perceived as acceptable by the participating stakeholders and will be pilot-tested in a randomized controlled trial.
在乳腺癌治疗期间及之后，体重增加的情况屡见不鲜。超重/肥胖的女性乳腺癌预后较差，且更易出现合并症。本研究描述了NutriLife研究的开发过程及其可接受性的定性评估，这是一项针对乳腺癌幸存者（BCS）的生活方式体重管理干预措施，包括饮食咨询和数字工具。该干预措施是依据医学研究理事会（MRC）框架开发的，系统文献综述和利益相关者的意见为其提供了参考。使用可接受性理论框架（TFA）对可接受性进行评估。共有22名超重/肥胖的BCS参加了焦点小组，5名希腊专门从事乳腺癌治疗的营养师/营养学家参加了半结构化访谈。使用主题分析法对数据进行进一步分析。利益相关者评估该干预措施在所有TFA结构方面都是可接受的。该干预措施的特点是具有支持性、易于调整、省时、组织有序、有益且由专业人员推动，潜在障碍包括个人时间有限、数字素养不足、自我护理不够以及缺乏投入。逐步提高目标可能会有所帮助且压力较小，而教育资源可增强对这些目标的关注，从而鼓励参与干预。确保保密性被视为促进健康的核心。NutriLife干预措施基于证据的共同参与式设计被参与的利益相关者认为是可接受的，并将在一项随机对照试验中进行试点测试。
