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个体或群体干预措施对肥胖成年人长期减肥更有效吗?系统评价。

Are individual or group interventions more effective for long-term weight loss in adults with obesity? A systematic review.

机构信息

Health Services Research Unit, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland.

出版信息

Clin Obes. 2022 Oct;12(5):e12539. doi: 10.1111/cob.12539. Epub 2022 Jun 28.

Abstract

Guidelines recommend individual and group interventions for weight loss, based on preference. Our 2009 systematic review compared long-term effectiveness of individual or group approaches to the same intervention, but there are new randomized controlled trials (RCTs) of high-quality data. We updated and expanded our previous systematic review. We searched Medline and Embase from 1966 to May 2021, and a clinical trial register from 1966 to 2017. Review Manager (5.4.1) was used to conduct meta-analysis. Ten RCTs were included. The primary outcome, mean weight change at final follow-up, was -1.33 kg (95% confidence interval CI: -2.04, -0.62; 10 trials, 2169 participants), favouring group interventions (p < .001). For the secondary outcomes, attainment of ≥5% body weight loss at final follow-up, the risk ratio (RR) was 1.36 (95% CI 1.05, 1.77; three trials, 1520 participants), favouring group interventions (p = .02); attrition at final follow-up was similar between group and individual arms of trials, RR 0.93 (95% CI 0.82, 1.07) (p = .31). Group interventions can be more effective than individual interventions for long-term weight loss in adults with obesity. However, few studies were included in the clinically relevant, secondary outcome measures. Research on delivering group processes in weight management is needed.

摘要

指南建议根据个人偏好选择个体或群体干预措施来进行减肥。我们 2009 年的系统评价比较了个体或群体方法对相同干预措施的长期效果,但有新的高质量数据的随机对照试验(RCT)。我们更新和扩展了之前的系统评价。我们检索了 Medline 和 Embase 从 1966 年到 2021 年 5 月,以及临床试验注册中心从 1966 年到 2017 年。使用 Review Manager(5.4.1)进行荟萃分析。纳入了 10 项 RCT。主要结局指标为最终随访时的平均体重变化,组间干预的体重减轻平均值为-1.33kg(95%置信区间 CI:-2.04,-0.62;10 项试验,2169 名参与者),这表明组间干预更有效(p<0.001)。次要结局指标为最终随访时达到体重减轻≥5%,组间干预的风险比(RR)为 1.36(95%置信区间 1.05,1.77;3 项试验,1520 名参与者),表明组间干预更有效(p=0.02);最终随访时的脱落率在组间和个体组间的试验中相似,RR 0.93(95% CI 0.82,1.07)(p=0.31)。在肥胖成年人的长期减肥中,组间干预可能比个体干预更有效。然而,在有临床意义的次要结局指标中,纳入的研究较少。需要对在体重管理中实施组间过程的研究进行研究。

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