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阻塞性睡眠呼吸暂停中气道床旁超声测量与筛查及严重程度评估工具的相关性:一项探索性研究

Correlation of Airway POCUS Measures with Screening and Severity Evaluation Tools in Obstructive Sleep Apnea: An Exploratory Study.

作者信息

Ravindranath Sapna, Ranganath Yatish S, Lemke Ethan, Behrens Matthew B, Marian Anil A, Kalagara Hari, Sadek Nada, Seering Melinda S, Wendt Linder, Ten Eyck Patrick, Sondekoppam Rakesh V

机构信息

Department of Anesthesia, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Department of Emergency Medicine, University of Michigan Health-West, Wyoming, MI 49519, USA.

出版信息

J Clin Med. 2025 Jul 9;14(14):4858. doi: 10.3390/jcm14144858.

Abstract

Obstructive Sleep Apnea (OSA) is a common occurrence in the perioperative patient population but is often undiagnosed. Point-of-Care Ultrasound (POCUS) has emerged as a promising tool for perioperative assessment; however, its effectiveness in detecting the presence or severity of OSA needs to be evaluated. We assessed the ability of airway POCUS as a screening and severity evaluation tool for OSA by examining its correlation with STOP-BANG scores and the Apnea-Hypopnea Index (AHI). Cross-sectional observational study. A single-center study in a tertiary care hospital between June 2020 to May 2021. Adult patients aged 18-65 with prior Polysomnography (PSG) for OSA workup were screened. The participants completed the STOP-BANG questionnaire and subsequently underwent POCUS examinations, either pre- or post-surgery. Ten different POCUS views previously used for evaluating OSA were acquired in a predefined sequence, with subsequent measurements of airway parameters. Generalized linear modeling was used to explore and assess the relationships between the measured parameters, STOP-BANG, and AHI scores (modeled continuously and categorized into risk levels of STOP-BANG and AHI). A total of 260 patients were screened, of which 142 were enrolled and 127 completed the scanning studies. The median AHI was 16.71, while the STOP-BANG scores were mostly between 5 and 6, indicating a moderate-to-high OSA risk in the study population. Notably, only neck circumference was significantly associated with AHI severity ( = 0.012), whereas none of the other POCUS measures were. Among the POCUS measures, significant associations with STOP-BANG scores were observed for the Tongue Cross-Sectional Area (T-CSA) ( = 0.002), Retro-Palatal Diameter (RPD) ( = 0.034), Distance Between Lingual Arteries (DLA) ( = 0.034), and Geniohyoid Muscle Thickness (GMT) ( = 0.040). Neck circumference is a more reliable predictor of OSA severity (AHI) compared to other POCUS measurements. Many of the POCUS measures had a good correlation with the STOP-BANG scores, highlighting the utility of POCUS as a screening tool for OSA rather than as a severity evaluation tool.

摘要

阻塞性睡眠呼吸暂停(OSA)在围手术期患者中很常见,但往往未被诊断出来。床旁超声(POCUS)已成为围手术期评估的一种有前景的工具;然而,其在检测OSA的存在或严重程度方面的有效性需要评估。我们通过检查气道POCUS与STOP-BANG评分和呼吸暂停低通气指数(AHI)的相关性,评估其作为OSA筛查和严重程度评估工具的能力。横断面观察性研究。2020年6月至2021年5月在一家三级护理医院进行的单中心研究。对年龄在18 - 65岁、之前因OSA检查接受过多导睡眠图(PSG)检查的成年患者进行筛查。参与者完成STOP-BANG问卷,随后在手术前或手术后接受POCUS检查。按照预定义顺序获取先前用于评估OSA的10种不同POCUS视图,随后测量气道参数。使用广义线性模型来探索和评估测量参数、STOP-BANG和AHI评分之间的关系(连续建模并分类为STOP-BANG和AHI的风险水平)。共筛查了260例患者,其中142例入组,127例完成扫描研究。AHI中位数为16.71,而STOP-BANG评分大多在5至6之间,表明研究人群中OSA风险为中度至高度。值得注意的是,只有颈围与AHI严重程度显著相关(= 0.012),而其他POCUS测量指标均无此关联。在POCUS测量指标中,舌横截面积(T-CSA)(= 0.002)、腭后直径(RPD)(= 0.034)、舌动脉间距(DLA)(= 0.034)和颏舌肌厚度(GMT)(= 0.040)与STOP-BANG评分存在显著关联。与其他POCUS测量相比,颈围是OSA严重程度(AHI)更可靠的预测指标。许多POCUS测量指标与STOP-BANG评分具有良好的相关性,突出了POCUS作为OSA筛查工具而非严重程度评估工具的实用性。

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本文引用的文献

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Comparison of awake respiratory control versus sleep obstructive sleep apnea endotypes.清醒呼吸控制与睡眠阻塞性睡眠呼吸暂停表型的比较。
J Appl Physiol (1985). 2024 Dec 1;137(6):1524-1534. doi: 10.1152/japplphysiol.00138.2024. Epub 2024 Oct 10.
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International Consensus Statement on Obstructive Sleep Apnea.国际阻塞性睡眠呼吸暂停共识声明。
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