Lim Jaehyun, Kim Byeonggeun
Department of Physical Therapy, Graduate School, Nambu University, Gwangju 62271, Republic of Korea.
Regional Health & Medical Center for Persons with Disabilities, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.
J Clin Med. 2025 Jul 14;14(14):4979. doi: 10.3390/jcm14144979.
: The importance of resistance training for functional recovery in Total Knee Arthroplasty (TKA) patients has been emphasized. Therefore, this systematic review and meta-analysis was conducted to analyze its effects on pain, muscle strength, and function in patients with TKA. : The following databases were used: PubMed, Web of Science, the Cochrane Library, and Embase. Randomized controlled trials that administered resistance training to patients undergoing TKA and measured pain, strength, and function were included. The risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool. Effect sizes were calculated using Hedges' g and are presented as Standardized Mean Differences (SMDs) with 95% Confidence Intervals (CIs). Subgroup analyses were conducted to determine the effect size based on the type and duration of the intervention. : The study selection process resulted in the inclusion of seven studies comprising a total of 439 participants. The bias assessment found that three studies had a low risk of bias and four had some concerns. Resistance training was effective in improving pain (SMD: 0.84, 95% CI: 0.11; 1.57, I: 89.6%), muscle strength (SMD: 1.03, 95% CI: 0.29; 1.77, I: 83.1%), self-reported function (SMD: 1.58, 95% CI: 0.15; 3.01, I: 93.1%), and performance-based function (SMD: 0.74, 95% CI: 0.38; 1.11, I: 68.9%). Subgroup analysis revealed significant differences in pain, strength, and performance-based function by comparison group, performance-based function by intervention duration, and self-reported function by intervention type. : Resistance training improves pain, muscle strength, and function in TKA patients. Additionally, resistance training appears particularly effective when implemented as a standalone intervention or for durations under 12 weeks. These findings suggest that the design of resistance training protocols should be considered in clinical practice.
全膝关节置换术（TKA）患者进行阻力训练对功能恢复的重要性已得到强调。因此，开展了这项系统评价和荟萃分析，以分析其对TKA患者疼痛、肌肉力量和功能的影响。使用了以下数据库：PubMed、科学网、考克兰图书馆和Embase。纳入了对接受TKA的患者进行阻力训练并测量疼痛、力量和功能的随机对照试验。使用考克兰偏倚风险2.0工具评估偏倚风险。效应量使用赫奇斯g进行计算，并以标准化均数差（SMD）和95%置信区间（CI）表示。进行亚组分析以根据干预类型和持续时间确定效应量。研究选择过程共纳入了7项研究，涉及439名参与者。偏倚评估发现，3项研究偏倚风险较低，4项研究存在一些问题。阻力训练在改善疼痛（SMD：0.84，95%CI：0.11；1.57，I²：89.6%）、肌肉力量（SMD：1.03，95%CI：0.29；1.77，I²：83.1%）、自我报告的功能（SMD：1.58，95%CI：0.15；3.01，I²：93.1%）和基于表现的功能（SMD：0.74，95%CI：0.38；1.11，I²：68.9%）方面有效。亚组分析显示，在疼痛、力量和基于表现的功能方面，不同比较组之间存在显著差异；在基于表现的功能方面，干预持续时间不同存在显著差异；在自我报告的功能方面，干预类型不同存在显著差异。阻力训练可改善TKA患者的疼痛、肌肉力量和功能。此外，当作为独立干预措施实施或持续时间在12周以内时，阻力训练似乎特别有效。这些发现表明，在临床实践中应考虑阻力训练方案的设计。
