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人工智能在糖尿病视网膜病变诊断与管理中的作用

The Role of Artificial Intelligence in the Diagnosis and Management of Diabetic Retinopathy.

作者信息

Ansari Areeb, Ansari Nabiha, Khalid Usman, Markov Daniel, Bechev Kristian, Aleksiev Vladimir, Markov Galabin, Poryazova Elena

机构信息

Faculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.

Department of General and Clinical Pathology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.

出版信息

J Clin Med. 2025 Jul 20;14(14):5150. doi: 10.3390/jcm14145150.

DOI:10.3390/jcm14145150
PMID:40725843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12296123/
Abstract

: Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes mellitus and a leading cause of vision impairment worldwide. Early detection and timely management are critical in preventing vision loss, yet current screening programs face challenges, including limited specialist availability and variability in diagnoses, particularly in underserved areas. This literature review explores the evolving role of artificial intelligence (AI) in enhancing the diagnosis, screening, and management of diabetic retinopathy. It examines AI's potential to improve diagnostic accuracy, accessibility, and patient outcomes through advanced machine-learning and deep-learning algorithms. : We conducted a non-systematic review of the published literature to explore advancements in the diagnostics of diabetic retinopathy. Relevant articles were identified by searching the PubMed and Google Scholar databases. Studies focusing on the application of artificial intelligence in screening, diagnosis, and improving healthcare accessibility for diabetic retinopathy were included. Key information was extracted and synthesized to provide an overview of recent progress and clinical implications. : Artificial intelligence holds transformative potential in diabetic retinopathy care by enabling earlier detection, improving screening coverage, and supporting individualized disease management. Continued research and ethical deployment will be essential to maximize AI's benefits and address challenges in real-world applications, ultimately improving global vision health outcomes.

摘要

糖尿病视网膜病变(DR)是糖尿病的一种进行性微血管并发症,也是全球视力损害的主要原因。早期检测和及时管理对于预防视力丧失至关重要,但目前的筛查项目面临挑战,包括专科医生数量有限以及诊断存在差异,尤其是在医疗服务不足的地区。这篇文献综述探讨了人工智能(AI)在加强糖尿病视网膜病变诊断、筛查和管理方面不断演变的作用。它研究了AI通过先进的机器学习和深度学习算法提高诊断准确性、可及性和患者治疗效果的潜力。我们对已发表的文献进行了非系统性综述,以探索糖尿病视网膜病变诊断方面的进展。通过搜索PubMed和谷歌学术数据库确定了相关文章。纳入了关注人工智能在糖尿病视网膜病变筛查、诊断以及改善医疗可及性方面应用的研究。提取并综合关键信息,以概述近期进展和临床意义。人工智能在糖尿病视网膜病变护理方面具有变革潜力,能够实现更早检测、提高筛查覆盖率并支持个性化疾病管理。持续的研究和符合伦理的应用对于最大化AI的益处以及应对实际应用中的挑战至关重要,最终改善全球视力健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014a/12296123/16097d34adda/jcm-14-05150-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014a/12296123/16097d34adda/jcm-14-05150-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014a/12296123/16097d34adda/jcm-14-05150-g001.jpg

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本文引用的文献

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Improving diabetic retinopathy screening using artificial intelligence: design, evaluation and before-and-after study of a custom development.利用人工智能改善糖尿病视网膜病变筛查:定制开发的设计、评估及前后对照研究
Front Digit Health. 2025 Jun 19;7:1547045. doi: 10.3389/fdgth.2025.1547045. eCollection 2025.
2
Deep learning for enhanced prediction of diabetic retinopathy: a comparative study on the diabetes complications data set.用于增强糖尿病视网膜病变预测的深度学习:对糖尿病并发症数据集的比较研究
Front Med (Lausanne). 2025 Jun 16;12:1591832. doi: 10.3389/fmed.2025.1591832. eCollection 2025.
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Development and validation of predictive models for diabetic retinopathy using machine learning.
使用机器学习开发和验证糖尿病视网膜病变预测模型
PLoS One. 2025 Feb 24;20(2):e0318226. doi: 10.1371/journal.pone.0318226. eCollection 2025.
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A deep learning-based ADRPPA algorithm for the prediction of diabetic retinopathy progression.一种基于深度学习的用于预测糖尿病视网膜病变进展的ADRPPA算法。
Sci Rep. 2024 Dec 30;14(1):31772. doi: 10.1038/s41598-024-82884-9.
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A Narrative Review of Ethical Issues in the Use of Artificial Intelligence Enabled Diagnostics for Diabetic Retinopathy.关于使用人工智能辅助诊断糖尿病视网膜病变的伦理问题的叙述性综述
J Eval Clin Pract. 2024 Nov 11. doi: 10.1111/jep.14237.
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Artificial Intelligence Applications in Diabetic Retinopathy: What We Have Now and What to Expect in the Future.人工智能在糖尿病视网膜病变中的应用:现状与未来展望。
Endocrinol Metab (Seoul). 2024 Jun;39(3):416-424. doi: 10.3803/EnM.2023.1913. Epub 2024 Jun 10.
7
Automated Machine Learning for Predicting Diabetic Retinopathy Progression From Ultra-Widefield Retinal Images.基于超广角视网膜图像的糖尿病视网膜病变进展预测的自动化机器学习。
JAMA Ophthalmol. 2024 Mar 1;142(3):171-177. doi: 10.1001/jamaophthalmol.2023.6318.
8
Artificial intelligence-supported diabetic retinopathy screening in Tanzania: rationale and design of a randomised controlled trial.坦桑尼亚人工智能辅助糖尿病视网膜病变筛查:一项随机对照试验的基本原理与设计
BMJ Open. 2024 Jan 25;14(1):e075055. doi: 10.1136/bmjopen-2023-075055.
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Autonomous artificial intelligence increases screening and follow-up for diabetic retinopathy in youth: the ACCESS randomized control trial.自主人工智能增加青少年糖尿病视网膜病变的筛查和随访:ACCESS 随机对照试验。
Nat Commun. 2024 Jan 11;15(1):421. doi: 10.1038/s41467-023-44676-z.
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