Konte Hasan Can, Dervis Emir, Yakut Idris, Aras Dursun
Department of Cardiology, Istanbul Medipol University, Istanbul 34815, Türkiye.
Department of Cardiology, Sincan Training and Research Hospital, Ankara 06949, Türkiye.
J Clin Med. 2025 Jul 21;14(14):5155. doi: 10.3390/jcm14145155.
Atrial fibrillation (AF) recurrence following catheter ablation remains a significant clinical challenge despite technological advancements, with recurrence rates in the range of 20-40%. While left atrial parameters have been extensively studied as predictors of recurrence, the contribution of right atrial mechanical function has received limited attention. The hypothesis that the combined assessment of right and left atrial strain parameters may provide superior predictive value represents an important clinical question with potential implications for post-ablation risk stratification and follow-up strategies. This single-center, retrospective cohort study included 100 consecutive adult patients who underwent AF ablation between May 2022 and June 2024 with at least one-year follow-up. Patients were divided into two groups: those with recurrence ( = 13) and those without recurrence ( = 87). A comprehensive echocardiographic assessment, including the speckle-tracking strain analysis of both atria, was performed. The median follow-up was 365 days [range: 150-912 days] in patients with recurrence. In the multivariable analysis, right ventricular diameter (OR: 0.74; 95% CI: 0.61-0.90; = 0.001), left ventricular end-diastolic volume (OR: 1.04; 95% CI: 1.00-1.08; = 0.022), and left ventricular global longitudinal strain rate (OR: 1.22; 95% CI: 1.05-1.40; = 0.007) emerged as independent predictors of recurrence. The significant association of right atrial longitudinal reservoir strain with recurrence in univariable analysis, although not retained as an independent predictor in the multivariable model, suggests the importance of comprehensive cardiac assessment including right heart parameters in predicting AF recurrence.
尽管技术不断进步,但导管消融术后房颤(AF)复发仍是一项重大的临床挑战,复发率在20%-40%之间。虽然左心房参数作为复发预测指标已得到广泛研究,但右心房机械功能的作用却受到的关注有限。联合评估右心房和左心房应变参数可能具有更高预测价值这一假设,是一个重要的临床问题,对消融术后风险分层和随访策略可能具有潜在影响。这项单中心回顾性队列研究纳入了100例在2022年5月至2024年6月期间接受房颤消融且至少随访一年的成年患者。患者分为两组:复发组(n = 13)和未复发组(n = 87)。进行了全面的超声心动图评估,包括对两个心房的斑点追踪应变分析。复发患者的中位随访时间为365天[范围:150 - 912天]。在多变量分析中,右心室直径(OR:0.74;95%CI:0.61 - 0.90;P = 0.001)、左心室舒张末期容积(OR:1.04;95%CI:1.00 - 1.08;P = 0.022)和左心室整体纵向应变率(OR:1.22;95%CI:1.05 - 1.40;P = 0.007)成为复发的独立预测因素。单变量分析中右心房纵向储备应变与复发有显著关联,尽管在多变量模型中未保留为独立预测因素,但这表明在预测房颤复发时,包括右心参数在内的全面心脏评估很重要。