Barilli Maria, Mandoli Giulia Elena, Sisti Nicolò, Dokollari Aleksander, Ghionzoli Nicolò, Soliman-Aboumarie Hatem, D'Ascenzi Flavio, Focardi Marta, Cavigli Luna, Pastore Maria Concetta, Cameli Matteo
Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Policlinico "Le Scotte", 53100 Siena, Italy.
Cardiology Unit, Electrophysiology Section, Gualdo Tadino Hospital, 06024 Gubbio, Italy.
J Cardiovasc Dev Dis. 2024 Jun 30;11(7):203. doi: 10.3390/jcdd11070203.
Pulmonary vein isolation (PVI) with catheter ablation (CA) represents an effective therapy for atrial fibrillation (AF). Unfortunately, it is still not exempt from severe complications. The balance of risks and benefits should be assessed, and a patient-tailored approach is desirable. So far, several clinical and cardiac imaging parameters have been evaluated to investigate pre- and post-procedural features that could help clinicians in the selection of patients at high risk of a poor outcome after CA. This clinical and systematic review analyses the potential role of new LA parameters, such as LA reservoir strain, to predict AF recurrence after CA therapy. Notably, LA reservoir strain gains substantial clinical importance in patients with paroxysmal AF and when a low CHADS2-VASc score is retrieved. LA reservoir strain provides data concerning the risk of AF recurrence after PVI and, thus, in the management of long-term medical therapy in this patient's group.
导管消融术（CA）进行肺静脉隔离（PVI）是治疗心房颤动（AF）的一种有效方法。不幸的是，它仍无法避免严重并发症。应评估风险与收益的平衡，采用针对患者的个体化方法是可取的。到目前为止，已经评估了几个临床和心脏成像参数，以研究术前和术后特征，这些特征可以帮助临床医生选择CA后预后不良风险高的患者。这项临床和系统评价分析了新的左心房（LA）参数，如LA储备应变，在预测CA治疗后AF复发方面的潜在作用。值得注意的是，LA储备应变在阵发性AF患者中以及当CHADS2-VASc评分较低时具有重要的临床意义。LA储备应变提供了有关PVI后AF复发风险的数据，因此，在该患者群体的长期药物治疗管理中具有重要意义。
